(Q40190309)

18 September 2017

title

alpha-Synuclein stimulates differentiation of osteosarcoma cells: relevance to down-regulation of proteasome activity (English)

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18 September 2017

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Masayo Fujita

1

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18 September 2017

Shuei Sugama

2

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18 September 2017

Masaaki Nakai

3

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18 September 2017

Takato Takenouchi

4

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18 September 2017

Jianshe Wei

5

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18 September 2017

Tomohiko Urano

6

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18 September 2017

Satoshi Inoue

7

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18 September 2017

Makoto Hashimoto

8

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18 September 2017

language of work or name

English

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publication date

22 December 2006

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Journal of Biological Chemistry

18 September 2017

number of pages

13

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based on heuristic

inferred from page(s)

published in

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18 September 2017

volume

282

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18 September 2017

issue

8

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18 September 2017

page(s)

5736-5748

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Alpha-synuclein in Lewy body disease and Alzheimer's disease

18 September 2017

cites work

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Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

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Identification of two distinct synucleins from human brain

21 January 2018

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Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

21 January 2018

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Evolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease

21 January 2018

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 January 2018

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beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

21 January 2018

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Identification, localization and characterization of the human gamma-synuclein gene

21 January 2018

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Overexpression of synuclein-gamma in pancreatic adenocarcinoma

21 January 2018

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Diagnostic potential in bladder cancer of a panel of tumor markers (calreticulin, gamma -synuclein, and catechol-o-methyltransferase) identified by proteomic analysis

21 January 2018

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Breast cancer-specific gene 1 interacts with the mitotic checkpoint kinase BubR1

21 January 2018

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Synuclein gamma inhibits the mitotic checkpoint function and promotes chromosomal instability of breast cancer cells

21 January 2018

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To die or grow: Parkinson's disease and cancer

21 January 2018

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Parkin gene alterations in hepatocellular carcinoma

21 January 2018

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Alterations of the tumor suppressor gene Parkin in non-small cell lung cancer

21 January 2018

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Discovery of Inhibitors that Elucidate the Role of UCH-L1 Activity in the H1299 Lung Cancer Cell Line

21 January 2018

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Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1)

21 January 2018

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DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras

21 January 2018

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DJ-1, a novel regulator of the tumor suppressor PTEN.

21 January 2018

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alpha-Synuclein is expressed in a variety of brain tumors showing neuronal differentiation.

21 January 2018

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Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas

21 January 2018

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Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary

21 January 2018

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NACP, a synaptic protein involved in Alzheimer's disease, is differentially regulated during megakaryocyte differentiation

21 January 2018

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Synuclein-1 is selectively up-regulated in response to nerve growth factor treatment in PC12 cells

21 January 2018

1 reference

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C-terminal alpha-synuclein immunoreactivity in structures other than Lewy bodies in neurodegenerative disorders

21 January 2018

1 reference

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Reduced neuritic outgrowth and cell adhesion in neuronal cells transfected with human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

Alpha-synuclein up-regulates expression of caveolin-1 and down-regulates extracellular signal-regulated kinase activity in B103 neuroblastoma cells: role in the pathogenesis of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

A soluble form of fibroblast growth factor receptor 2 (FGFR2) with S252W mutation acts as an efficient inhibitor for the enhanced osteoblastic differentiation caused by FGFR2 activation in Apert syndrome

21 January 2018

1 reference

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Induction of protein degradation in skeletal muscle by a phorbol ester involves upregulation of the ubiquitin-proteasome proteolytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

Rat alpha-synuclein interacts with Tat binding protein 1, a component of the 26S proteasomal complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

21 January 2018

1 reference

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Proteasomal inhibition by alpha-synuclein filaments and oligomers.

21 January 2018

1 reference

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The roles of intracellular protein-degradation pathways in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

beta-Synuclein reduces proteasomal inhibition by alpha-synuclein but not gamma-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

Phosphorylation of 20S proteasome alpha subunit C8 (alpha7) stabilizes the 26S proteasome and plays a role in the regulation of proteasome complexes by gamma-interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

Alpha-synuclein alters proteasome function, protein synthesis, and stationary phase viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

Cell cycle aberrations by alpha-synuclein over-expression and cyclin B immunoreactivity in Lewy bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

alpha-Synuclein affects the MAPK pathway and accelerates cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

Expanding insights of mitochondrial dysfunction in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606175200

21 January 2018

Identifiers

DOI

10.1074/JBC.M606175200

1 reference

18 September 2017

1 reference