(Q40196772)

18 September 2017

The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains (English)

1 reference

18 September 2017

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26682033%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Oleg Fedorov

2

1 reference

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9 June 2020

Panagis Filippakopoulos

3

1 reference

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9 June 2020

David S Hewings

7

1 reference

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9 June 2020

Stefan Knapp

11

1 reference

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9 June 2020

Paul E. Brennan

12

1 reference

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9 June 2020

5

Martin Philpott

1 reference

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9 June 2020

9

Tom D Heightman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26682033%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

6

Sarah Picaud

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26682033%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Duncan Hay

1

1 reference

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9 June 2020

Sarah Martin

4

1 reference

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9 June 2020

Sagar Uttakar

8

1 reference

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9 June 2020

language of work or name

1 reference

1 January 2013

1 reference

18 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26682033%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

4

1 reference

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9 June 2020

page(s)

140-144

1 reference

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9 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26682033%20AND%20SRC:MED&resulttype=core&format=json

The bromodomain interaction module

9 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

Histone recognition and large-scale structural analysis of the human bromodomain family

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

From ApoA1 upregulation to BET family bromodomain inhibition: discovery of I-BET151.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

Fragment-based discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

Fragment-based discovery of bromodomain inhibitors part 1: inhibitor binding modes and implications for lead discovery

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

Bromodomains as therapeutic targets

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

Suppression of inflammation by a synthetic histone mimic

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

Selective inhibition of BET bromodomains

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

The development of benzimidazoles as selective rho kinase inhibitors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678575

20 August 2018

Identifiers

DOI

10.1039/C2MD20189E

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26682033%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

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9 June 2020

1 reference

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