(Q40209443)

18 September 2017

Telomerase-independent regulation of ATR by human telomerase RNA. (English)

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18 September 2017

8

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18 September 2017

Martijn Kedde

1

1 reference

18 September 2017

Carlos le Sage

2

1 reference

18 September 2017

Anja Duursma

3

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18 September 2017

Eitan Zlotorynski

4

1 reference

18 September 2017

Bart van Leeuwen

5

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18 September 2017

Wouter Nijkamp

6

1 reference

18 September 2017

Roderick Beijersbergen

7

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18 September 2017

language of work or name

English

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publication date

10 November 2006

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Journal of Biological Chemistry

18 September 2017

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18 September 2017

281

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18 September 2017

40503-40514

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18 September 2017

52

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The serial cultivation of human diploid cell strains

18 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Human telomerase and its regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Telomeres shorten during ageing of human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

A DNA damage checkpoint response in telomere-initiated senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

DNA damage foci at dysfunctional telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Specific association of human telomerase activity with immortal cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

A survey of telomerase activity in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Reverse transcriptase motifs in the catalytic subunit of telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Telomerase maintains telomere structure in normal human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

The RNA component of human telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Secondary structure of vertebrate telomerase RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

A telomerase component is defective in the human disease dyskeratosis congenita

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Expression of telomerase RNA component correlates with the MIB-1 proliferation index in ependymomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Both transcriptional and posttranscriptional mechanisms regulate human telomerase template RNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

High telomerase RNA expression level is an adverse prognostic factor for favorable-histology Wilms' tumor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Functional links between telomeres and proteins of the DNA-damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Reciprocal association of the budding yeast ATM-related proteins Tel1 and Mec1 with telomeres in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Functional human telomeres are recognized as DNA damage in G2 of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

ATM and ATR make distinct contributions to chromosome end protection and the maintenance of telomeric DNA in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Inhibition of telomerase limits the growth of human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Stable suppression of tumorigenicity by virus-mediated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

A generic protein purification method for protein complex characterization and proteome exploration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Stable RNA interference (RNAi) as an option for anti-bcr-abl therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

The molecular basis of common and rare fragile sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

ATR Regulates Fragile Site Stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

ATR and ATM regulate the timing of DNA replication origin firing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Hypervariable ultra-long telomeres in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Developmental and tissue-specific regulation of mouse telomerase and telomere length

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Different telomere damage signaling pathways in human and mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

The tumor-suppressive functions of the human INK4A locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607676200

21 January 2018

Identifiers

DOI

10.1074/JBC.M607676200

1 reference

18 September 2017

1 reference