(Q40213412)

18 September 2017

Increased expression of SKP2 and phospho-MAPK/ERK1/2 and decreased expression of p27 during tumor progression of cervical neoplasms (English)

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18 September 2017

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Tzu-Ping Chen

1

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18 September 2017

Chien-Ming Chen

2

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18 September 2017

Hsueh-Wen Chang

3

1 reference

18 September 2017

Jyh-Seng Wang

4

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18 September 2017

Wei-Chi Chang

5

1 reference

18 September 2017

Su-In Hsu

6

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18 September 2017

Chung-Lung Cho

7

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18 September 2017

language of work or name

English

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publication date

31 October 2006

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18 September 2017

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18 September 2017

104

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18 September 2017

516-523

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18 September 2017

3

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Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

18 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Skp2 is oncogenic and overexpressed in human cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Deregulated degradation of the cdk inhibitor p27 and malignant transformation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Prognostic significance of p27(Kip1) expression in colorectal cancer: a clinico-pathological characterization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Low expression levels of p27 correlate with loco-regional recurrence in nasopharyngeal carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Expression and prognostic roles of the G1-S modulators in hepatocellular carcinoma: p27 independently predicts the recurrence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Expression of cyclin E and p27(KIP1) in cervical carcinoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

How MAP kinases are regulated

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Parallel signal processing among mammalian MAPKs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Transcriptional regulation by extracellular signals: mechanisms and specificity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

The MAPK signaling cascade

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Targeting the mitogen-activated protein kinase cascade to treat cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

The ubiquitin-proteasome pathway and its role in cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Role of the F-box protein Skp2 in lymphomagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Skp2 protein expression in soft tissue sarcomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Elevated S-phase kinase-associated protein 2 protein expression in acute myelogenous leukemia: its association with constitutive phosphorylation of phosphatase and tensin homologue protein and poor prognosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Expression of the cell cycle regulator p27(Kip1) in normal squamous epithelium, cervical intraepithelial neoplasia, and invasive squamous cell carcinoma of the uterine cervix. Immunohistochemistry and functional aspects of p27(Kip1)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Aberrant expression of p21(WAF1/CIP1) and p27(KIP1) in cervical carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Down-regulation of p27 is associated with malignant transformation and aggressive phenotype of cervical neoplasms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Overexpression of Skp2 in carcinoma of the cervix does not correlate inversely with p27 expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

Transcriptional activation of H- and N-ras oncogenes in human cervical cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.09.015

10.1016/J.YGYNO.2006.09.015

7 January 2021

Identifiers

DOI

1 reference

18 September 2017

1 reference