(Q40219956)

18 September 2017

title

Nucleocytoplasmic shuttling of the retinoblastoma tumor suppressor protein via Cdk phosphorylation-dependent nuclear export (English)

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18 September 2017

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author name string

Wan Jiao

1

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18 September 2017

Huei-Min Lin

3

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18 September 2017

Miroslav Dundr

4

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18 September 2017

Sushil G Rane

5

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18 September 2017

language of work or name

English

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publication date

16 October 2006

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Journal of Biological Chemistry

18 September 2017

published in

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18 September 2017

volume

281

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18 September 2017

issue

49

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18 September 2017

page(s)

38098-38108

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To cycle or not to cycle: a critical decision in cancer.

18 September 2017

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A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity

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The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing

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G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment

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The retinoblastoma gene product is bound in the nucleus in early G1 phase

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Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

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Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence

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Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.

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Retinoblastoma Tumor Suppressor: Analyses of Dynamic Behavior in Living Cells Reveal Multiple Modes of Regulation

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C-terminal truncation of the retinoblastoma gene product leads to functional inactivation

21 January 2018

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Identification of a growth suppression domain within the retinoblastoma gene product

21 January 2018

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Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover

21 January 2018

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Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

21 January 2018

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The APC tumour suppressor has a nuclear export function.

21 January 2018

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Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle

21 January 2018

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Exportin 1 (Crm1p) is an essential nuclear export factor

21 January 2018

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Retinoblastoma protein partners

21 January 2018

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Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus

21 January 2018

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An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

21 January 2018

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Phosphate-regulated inactivation of the kinase PHO80-PHO85 by the CDK inhibitor PHO81.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M605271200

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18 September 2017

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