(Q40224086)

18 September 2017

title

The ubiquitin- and proteasome-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs (English)

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ubiquitin-proteasome system

18 September 2017

main subject

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author

Wolfgang Dubiel

9

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18 September 2017

Heiko Neuss

1

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18 September 2017

Xiaohua Huang

2

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18 September 2017

Bettina K J Hetfeld

3

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18 September 2017

Rupal Deva

4

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18 September 2017

Petra Henklein

5

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18 September 2017

Santosh Nigam

6

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18 September 2017

Julian W Mall

7

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18 September 2017

Wolfgang Schwenk

8

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18 September 2017

publication date

11 April 2007

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Journal of Molecular Medicine

18 September 2017

published in

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18 September 2017

volume

85

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issue

9

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18 September 2017

page(s)

961-970

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https://scigraph.springernature.com/pub.10.1007/s00109-007-0197-y

18 September 2017

exact match

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cites work

Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response

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12 December 2020

Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells

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12 December 2020

Valdecoxib: assessment of cyclooxygenase-2 potency and selectivity

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12 December 2020

IGF-II/IGF-I receptor pathway up-regulates COX-2 mRNA expression and PGE2 synthesis in Caco-2 human colon carcinoma cells

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12 December 2020

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12 December 2020

Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p

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12 December 2020

Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents?

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12 December 2020

N-[[(5-methyl-3-phenylisoxazol-4-yl)-phenyl]sulfonyl]propanamide, sodium salt, parecoxib sodium: A potent and selective inhibitor of COX-2 for parenteral administration

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12 December 2020

Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery

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12 December 2020

Ubiquitin-dependent degradation of Id1 and Id3 is mediated by the COP9 signalosome

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12 December 2020

Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo

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12 December 2020

A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin

1 reference

12 December 2020

Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands

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12 December 2020

Function and regulation of cullin-RING ubiquitin ligases

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12 December 2020

Purification method of the COP9 signalosome from human erythrocytes

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12 December 2020

A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.

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12 December 2020

The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1

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12 December 2020

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

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12 December 2020

The COX-2 inhibitors--an update

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12 December 2020

Differential regulation of cyclooxygenases 1 and 2 by interleukin-1 beta, tumor necrosis factor-alpha, and transforming growth factor-beta 1 in human lung fibroblasts

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12 December 2020

COX2 expression, angiogenesis, proliferation and survival in Barrett's cancer

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12 December 2020

COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

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12 December 2020

Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome

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12 December 2020

Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.

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12 December 2020

The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing

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12 December 2020

Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development.

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12 December 2020

Characterization of celecoxib and valdecoxib binding to cyclooxygenase.

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12 December 2020

Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase

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12 December 2020

Cox-2 inhibitors: today and tomorrow

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12 December 2020

Anticancer potential of curcumin: preclinical and clinical studies.

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12 December 2020

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

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12 December 2020

Proteasome inhibition in neuronal cells induces a proinflammatory response manifested by upregulation of cyclooxygenase-2, its accumulation as ubiquitin conjugates, and production of the prostaglandin PGE(2).

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12 December 2020

Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors

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12 December 2020

Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways.

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12 December 2020

Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms

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12 December 2020

The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase

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12 December 2020

Consequences of COP9 signalosome and 26S proteasome interaction.

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12 December 2020

Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells

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12 December 2020

10.1007/S00109-007-0197-Y

Identifiers

DOI

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18 September 2017

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