(Q40234429)

18 September 2017

title

Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells (English)

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18 September 2017

Suniti Misra

1

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18 September 2017

Bryan P Toole

series ordinal

2

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18 September 2017

Shibnath Ghatak

series ordinal

3

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18 September 2017

language of work or name

English

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publication date

7 September 2006

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Journal of Biological Chemistry

18 September 2017

published in

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18 September 2017

volume

281

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18 September 2017

issue

46

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18 September 2017

page(s)

34936-34941

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Oncogenic kinase signalling

18 September 2017

cites work

1 reference

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Intracellular hyaluronan: a new frontier for inflammation?

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Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.

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21 January 2018

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Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth

21 January 2018

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EGF receptor modifies cellular responses to hyaluronan in glioblastoma cell lines

21 January 2018

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Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells.

21 January 2018

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Regulation of MDR1 expression and drug resistance by a positive feedback loop involving hyaluronan, phosphoinositide 3-kinase, and ErbB2.

21 January 2018

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Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway

21 January 2018

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Use of the dissociating enzyme thermolysin to generate viable human normal intestinal epithelial cell cultures

21 January 2018

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Hyaluronan binding by cell surface CD44.

21 January 2018

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Hyaluronan oligosaccharides induce CD44 cleavage and promote cell migration in CD44-expressing tumor cells

21 January 2018

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Tumor cells enhance their own CD44 cleavage and motility by generating hyaluronan fragments

21 January 2018

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Engagement of CD44 promotes Rac activation and CD44 cleavage during tumor cell migration.

21 January 2018

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Constitutive and induced CD44 shedding by ADAM-like proteases and membrane-type 1 matrix metalloproteinase.

21 January 2018

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CD44 attenuates metastatic invasion during breast cancer progression

21 January 2018

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Overexpression of hyaluronan synthase-2 reduces the tumorigenic potential of glioma cells lacking hyaluronidase activity.

21 January 2018

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Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncogenic malignant transformation.

21 January 2018

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CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion

21 January 2018

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Concurrent expression of hyaluronan biosynthetic and processing enzymes promotes growth and vascularization of prostate tumors in mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.C600138200

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18 September 2017

1 reference