(Q40258100)

18 September 2017

title

IFN-λ3, not IFN-λ4, likely mediates IFNL3-IFNL4 haplotype-dependent hepatic inflammation and fibrosis (English)

1 reference

18 September 2017

12

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5 June 2020

Thomas Berg

5

1 reference

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5 June 2020

William L. Irving

7

1 reference

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5 June 2020

David Sheridan

9

1 reference

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5 June 2020

Henning Grønbæk

10

1 reference

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5 June 2020

Mark W Douglas

24

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5 June 2020

Elizabeth Powell

26

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5 June 2020

Manuel Romero-Gomez

27

1 reference

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5 June 2020

1

Mohammed Eslam

1 reference

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5 June 2020

8

Gregory J Dore

1 reference

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5 June 2020

author name string

Duncan McLeod

2

1 reference

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5 June 2020

Kebitsaone Simon Kelaeng

3

1 reference

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5 June 2020

Alessandra Mangia

4

1 reference

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5 June 2020

Khaled Thabet

6

1 reference

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5 June 2020

Maria Lorena Abate

11

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5 June 2020

Ulrich Spengler

14

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5 June 2020

Angela Rojas

15

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5 June 2020

David R Booth

16

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5 June 2020

Martin Weltman

17

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5 June 2020

Lindsay Mollison

18

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5 June 2020

Wendy Cheng

19

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5 June 2020

Stephen Riordan

20

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5 June 2020

Hema Mahajan

21

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5 June 2020

Janett Fischer

22

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5 June 2020

Jacob Nattermann

23

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5 June 2020

Christopher Liddle

25

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5 June 2020

Jacob George

28

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5 June 2020

International Liver Disease Genetics Consortium (ILDGC)

29

1 reference

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5 June 2020

Elisabetta Bugianesi

13

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5 June 2020

language of work or name

English

0 references

publication date

10 April 2017

1 reference

18 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394349%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

49

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5 June 2020

issue

5

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5 June 2020

page(s)

795-800

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IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes

5 June 2020

cites work

1 reference

Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease.

21 January 2018

1 reference

FibroGENE: A gene-based model for staging liver fibrosis

21 January 2018

1 reference

A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

21 January 2018

1 reference

The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs

21 January 2018

1 reference

Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ

21 January 2018

1 reference

Guarding the frontiers: the biology of type III interferons

21 January 2018

1 reference

Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection

21 January 2018

1 reference

Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections

21 January 2018

1 reference

HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons

21 January 2018

1 reference

IL-29 is the dominant type III interferon produced by hepatocytes during acute hepatitis C virus infection

21 January 2018

1 reference

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

21 January 2018

1 reference

IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

21 January 2018

1 reference

Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

21 January 2018

1 reference

Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study

21 January 2018

1 reference

Type III interferons, IL-28 and IL-29, are increased in chronic HCV infection and induce myeloid dendritic cell-mediated FoxP3+ regulatory T cells

21 January 2018

1 reference

Association of serum IFN-λ3 with inflammatory and fibrosis markers in patients with chronic hepatitis C virus infection.

21 January 2018

1 reference

IFN-λ Inhibits MiR-122 Transcription through a Stat3-HNF4α Inflammatory Feedback Loop in an IFN-α Resistant HCV Cell Culture System

21 January 2018

1 reference

Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis

21 January 2018

1 reference

Impairment of type I but not type III IFN signaling by hepatitis C virus infection influences antiviral responses in primary human hepatocytes

21 January 2018

1 reference

Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin-28B genotypes

21 January 2018

1 reference

Interferon-lambda serum levels in hepatitis C.

21 January 2018

1 reference

Interferon-induced gene expression is a stronger predictor of treatment response than IL28B genotype in patients with hepatitis C.

21 January 2018

1 reference

Human blood dendritic cell antigen 3 (BDCA3)(+) dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus

21 January 2018

1 reference

Ex vivo induction of IFN-λ3 by a TLR7 agonist determines response to Peg-IFN/ribavirin therapy in chronic hepatitis C patients

21 January 2018

1 reference

Hepatitis C virus kinetics by administration of pegylated interferon-α in human and chimeric mice carrying human hepatocytes with variants of the IL28B gene

21 January 2018

1 reference

IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C.

21 January 2018

1 reference

Impact of IL28B gene polymorphisms on interferon-λ3 plasma levels during pegylated interferon-α/ribavirin therapy for chronic hepatitis C in patients coinfected with HIV

21 January 2018

1 reference

IL28B genetic variation is associated with spontaneous clearance of hepatitis C virus, treatment response, serum IL-28B levels in Chinese population

21 January 2018

1 reference

IFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearance

21 January 2018

1 reference

Expression of Interferon Lambda 4 Is Associated with Reduced Proliferation and Increased Cell Death in Human Hepatic Cells

21 January 2018

1 reference

Interferon-λ4 is a cell-autonomous type III interferon associated with pre-treatment hepatitis C virus burden

21 January 2018

1 reference

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses

21 January 2018

1 reference

Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes

21 January 2018

1 reference

Comparison of functional variants in IFNL4 and IFNL3 for association with HCV clearance

21 January 2018

1 reference

Rates and risk factors of liver fibrosis progression in patients with chronic hepatitis c.

21 January 2018

1 reference

Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells.

21 January 2018

1 reference

Liver fibrosis and repair: immune regulation of wound healing in a solid organ

21 January 2018

1 reference

Soluble CD163, a macrophage activation marker, is independently associated with fibrosis in patients with chronic viral hepatitis B and C.

21 January 2018

1 reference

An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group

21 January 2018

1 reference

IFNL3 polymorphisms predict response to therapy in chronic hepatitis C genotype 2/3 infection

21 January 2018

1 reference

Haploview: analysis and visualization of LD and haplotype maps

21 January 2018

1 reference