(Q40263710)

English

Nonsecreted insulin-like growth factor binding protein-3 (IGFBP-3) can induce apoptosis in human prostate cancer cells by IGF-independent mechanisms without being concentrated in the nucleus.

scientific article published on 22 June 2006

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Nonsecreted insulin-like growth factor binding protein-3 (IGFBP-3) can induce apoptosis in human prostate cancer cells by IGF-independent mechanisms without being concentrated in the nucleus (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

based on heuristic

inferred from title

prostate cancer

1 reference

based on heuristic

inferred from title

Malgorzata Wiench

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

Nisan Bhattacharyya

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Klaus Pechhold

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Hanief Shahjee

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Giovanna Zappala

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Cem Elbi

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Bruce Raaka

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Jiang Hong

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Matthew M Rechler

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

language of work or name

0 references

publication date

22 June 2006

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Journal of Biological Chemistry

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

281

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

34

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

24588-24601

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Cellular actions of the insulin-like growth factor binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Transfection of human insulin-like growth factor-binding protein 3 gene inhibits cell growth and tumorigenicity: a cell culture model for lung cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Combination therapy of insulin-like growth factor binding protein-3 and retinoid X receptor ligands synergize on prostate cancer cell apoptosis in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Reduced expression of insulin-like growth factor binding protein-3 and its promoter hypermethylation in human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Novel promoter polymorphism in insulin-like growth factor-binding protein-3: correlation with serum levels and interaction with known regulators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Loss of HOXC6 expression induces apoptosis in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Characterization of a novel positive transcription regulatory element that differentially regulates the insulin-like growth factor binding protein-3 (IGFBP-3) gene in senescent cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Human papillomavirus type 16 E7 oncoprotein binds and inactivates growth-inhibitory insulin-like growth factor binding protein 3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Transforming growth factor-beta-induced cell growth inhibition in human breast cancer cells is mediated through insulin-like growth factor-binding protein-3 action.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Induction of the growth inhibitor IGF-binding protein 3 by p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Functional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by tumor specific methylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Insulin-like growth factor binding protein-3 mediates cytokine-induced mesangial cell apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

The C terminus of p53 family proteins is a cell fate determinant

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Antiproliferative effects of insulin-like growth factor-binding protein-3 in mesenchymal chondrogenic cell line RCJ3.1C5.18. relationship to differentiation stage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

The human insulin-like growth factor (IGF) binding protein-3 inhibits the growth of fibroblasts with a targeted disruption of the IGF-I receptor gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Insulin-like growth factor (IGF)-binding protein-3 mutants that do not bind IGF-I or IGF-II stimulate apoptosis in human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Identification of STAT-1 as a molecular target of IGFBP-3 in the process of chondrogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Insulin-like growth factor (IGF) binding protein-3 attenuates prostate tumor growth by IGF-dependent and IGF-independent mechanisms.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Cloning and expression of the growth hormone-dependent insulin-like growth factor-binding protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Cellular growth inhibition by IGFBP-3 and TGF-beta1 requires LRP-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Insulin-like growth factor binding protein (IGFBP) signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Nuclear localization signal in insulin-like growth factor-binding protein type 3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Intranuclear localization of insulin-like growth factor binding protein-3 (IGFBP-3) during cell division in human keratinocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 share a common nuclear transport pathway in T47D human breast carcinoma cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Direct functional interactions between insulin-like growth factor-binding protein-3 and retinoid X receptor-alpha regulate transcriptional signaling and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Cellular internalization of insulin-like growth factor binding protein-3: distinct endocytic pathways facilitate re-uptake and nuclear localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Trafficking and signaling pathways of nuclear localizing protein ligands and their receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

IGF-binding protein-3-induced growth inhibition and apoptosis do not require cell surface binding and nuclear translocation in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Structural determinants of ligand and cell surface binding of insulin-like growth factor-binding protein-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Signaling through the Smad pathway by insulin-like growth factor-binding protein-3 in breast cancer cells. Relationship to transforming growth factor-beta 1 signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Oligosaccharyltransferase: a complex multisubunit enzyme of the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Programmed cell death: alive and well in the new millennium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Heparin inhibition of insulin-like growth factor-binding protein-3 binding to human fibroblasts and rat glioma cells: role of heparan sulfate proteoglycans.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

How cells die: apoptosis pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Insulin-like growth factor-binding protein 3 induces caspase-dependent apoptosis through a death receptor-mediated pathway in MCF-7 human breast cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Enhancement of tumor necrosis factor-alpha-induced growth inhibition by insulin-like growth factor-binding protein-5 (IGFBP-5), but not IGFBP-3 in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Intracrine regulation at the nucleus--a further mechanism of growth factor activity?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Human basic fibroblast growth factor gene encodes four polypeptides: three initiate translation from non-AUG codons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Multiple forms of bFGF: differential nuclear and cell surface localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Evidence of a novel intracrine mechanism in angiotensin II-induced cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Differential modulation of cell phenotype by different molecular weight forms of basic fibroblast growth factor: possible intracellular signaling by the high molecular weight forms.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Insulin-like growth factor-binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Expression of a new type high molecular weight receptor (type V receptor) of transforming growth factor beta in normal and transformed cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Growth inhibition by insulin-like growth factor-binding protein-3 in T47D breast cancer cells requires transforming growth factor-beta (TGF-beta ) and the type II TGF-beta receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Insulin-like growth factor-independent effects mediated by a C-terminal metal-binding domain of insulin-like growth factor binding protein-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Signaling on the endocytic pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Caspase-8 in apoptosis: the beginning of "the end"?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

The 16-kDa Proteolytic Fragment of Insulin-Like Growth Factor (IGF) Binding Protein-3 Inhibits the Mitogenic Action of Fibroblast Growth Factor on Mouse Fibroblasts with a Targeted Disruption of the Type 1 IGF Receptor Gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Mechanisms of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509463200

21 January 2018

Identifiers

10.1074/JBC.M509463200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793770%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40263710&oldid=1966866107"