(Q40271687)

19 September 2017

title

JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport (English)

1 reference

19 September 2017

Gerardo Morfini

1

1 reference

19 September 2017

Gustavo Pigino

2

1 reference

19 September 2017

Györgyi Szebenyi

3

1 reference

19 September 2017

Yimei You

4

1 reference

19 September 2017

Sarah Pollema

5

1 reference

19 September 2017

Scott T Brady

6

1 reference

19 September 2017

language of work or name

English

0 references

publication date

4 June 2006

1 reference

19 September 2017

1 reference

19 September 2017

volume

9

1 reference

19 September 2017

issue

7

1 reference

19 September 2017

page(s)

907-916

1 reference

https://scigraph.springernature.com/pub.10.1038/nn1717

19 September 2017

exact match

0 references

cites work

Glutamine repeats and neurodegeneration

1 reference

Polyglutamine expansion diseases: failing to deliver

21 January 2018

1 reference

Spinal and bulbar muscular atrophy: a trinucleotide-repeat expansion neurodegenerative disease

21 January 2018

1 reference

Biochemical and molecular characterization of diseases linked to motor proteins

21 January 2018

1 reference

Kinesin motors and disease

21 January 2018

1 reference

Mutations in dynein link motor neuron degeneration to defects in retrograde transport

21 January 2018

1 reference

A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10)

21 January 2018

1 reference

Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila

21 January 2018

1 reference

Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.

21 January 2018

1 reference

Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport

21 January 2018

1 reference

Kinesin-mediated organelle translocation revealed by specific cellular manipulations

21 January 2018

1 reference

Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

21 January 2018

1 reference

Fast axonal transport misregulation and Alzheimer's disease

21 January 2018

1 reference

Castration restores function and neurofilament alterations of aged symptomatic males in a transgenic mouse model of spinal and bulbar muscular atrophy.

21 January 2018

1 reference

Polyglutamine protein aggregation and toxicity are linked to the cellular stress response

21 January 2018

1 reference

Kennedy's disease. Phosphorylation of the polyglutamine-expanded form of androgen receptor regulates its cleavage by caspase-3 and enhances cell death

21 January 2018

1 reference

A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm

21 January 2018

1 reference

Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis

21 January 2018

1 reference

Neurofilament protein synthesis and phosphorylation

21 January 2018

1 reference

A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons

21 January 2018

1 reference

A small molecule-kinase interaction map for clinical kinase inhibitors

21 January 2018

1 reference

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

21 January 2018

1 reference

Identification of the critical features of a small peptide inhibitor of JNK activity

21 January 2018

1 reference

Protein aggregation and neurodegenerative disease

21 January 2018

1 reference

Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration

21 January 2018

1 reference

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

21 January 2018

1 reference

Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

21 January 2018

1 reference

Clinical features and skewed X-chromosome inactivation in female carriers of X-linked recessive spinal and bulbar muscular atrophy

21 January 2018

1 reference

Regulation of androgen receptor levels: implications for prostate cancer progression and therapy

21 January 2018

1 reference

A mouse model of spinal and bulbar muscular atrophy.

21 January 2018

1 reference

Expression of expanded repeat androgen receptor produces neurologic disease in transgenic mice.

21 January 2018

1 reference

Retardation in the slow axonal transport of cytoskeletal elements during maturation and aging

21 January 2018

1 reference

Role of JNK activation in apoptosis: a double-edged sword

21 January 2018

1 reference

Reduced axonal transport of the G4 molecular form of acetylcholinesterase in the rat sciatic nerve during aging

21 January 2018

1 reference

Diseases of unstable repeat expansion: mechanisms and common principles

21 January 2018

1 reference

Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization

21 January 2018

1 reference

Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death

21 January 2018

1 reference

In vitro translation of androgen receptor cRNA results in an activated androgen receptor protein

21 January 2018

1 reference

A and B forms of the androgen receptor are expressed in a variety of human tissues

21 January 2018

1 reference

7 January 2021

Regulation of kinesin: implications for neuronal development

1 reference

7 January 2021

Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport

1 reference

7 January 2021

Phosphorylation of neuronal kinesin heavy and light chains in vivo

1 reference

7 January 2021

c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons.

1 reference

7 January 2021

Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons.

1 reference

7 January 2021

Expression of X-linked bulbospinal muscular atrophy (Kennedy disease) in two homozygous women

1 reference

7 January 2021

Binding of 7 alpha, 17 alpha-dimethyl-19-nortestosterone (mibolerone) to androgen and progesterone receptors in human and animal tissues

1 reference

7 January 2021

Androgen receptor with elongated polyglutamine tract forms aggregates that alter axonal trafficking and mitochondrial distribution in motor neuronal processes

1 reference

7 January 2021

Identifiers

DOI

10.1038/NN1717

1 reference

Dimensions Publication ID

19 September 2017

1044780618

0 references

1 reference