(Q40277097)

English

Effects of antipsychotic drugs on I(to), I (Na), I (sus), I (K1), and hERG: QT prolongation, structure activity relationship, and network analysis

scientific article published on 25 May 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Effects of antipsychotic drugs on I(to), I (Na), I (sus), I (K1), and hERG: QT prolongation, structure activity relationship, and network analysis (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

2

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Europe PubMed Central

PubMed publication ID

19 September 2017

Charles M. Beasley

object named as

Charles M Beasley

7

0 references

author name string

William J Crumb

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

R Dustan Sarazan

3

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

James H Wikel

4

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Steven A Wrighton

5

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Europe PubMed Central

PubMed publication ID

19 September 2017

Christopher Carlson

6

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

publication date

25 May 2006

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Pharmaceutical Research

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Europe PubMed Central

PubMed publication ID

19 September 2017

23

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Europe PubMed Central

PubMed publication ID

19 September 2017

6

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Europe PubMed Central

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19 September 2017

1133-1143

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Europe PubMed Central

PubMed publication ID

19 September 2017

Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit

1 reference

https://api.crossref.org/works/10.1007%2FS11095-006-0070-7

21 January 2018

Cardiac arrhythmia and haloperidol

1 reference

https://api.crossref.org/works/10.1007%2FS11095-006-0070-7

21 January 2018

Mechanism of block and identification of the verapamil binding domain to HERG potassium channels

1 reference

https://api.crossref.org/works/10.1007%2FS11095-006-0070-7

21 January 2018

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drugs, QT interval abnormalities and ventricular arrhythmias.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Torsades de pointes ventricular tachyarrhythmia associated with haloperidol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A structural basis for drug-induced long QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The significance of QT interval in drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac conduction and rhythm disturbances following suicidal ingestion of mesoridazine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimal requirements for high affinity and use-dependent block of skeletal muscle sodium channel by N-benzyl analogs of tocainide-like compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predicting undesirable drug interactions with promiscuous proteins in silico

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partitioning of thioridazine and mesoridazine in human blood fractions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug binding to HERG channels: evidence for a 'non-aromatic' binding site for fluvoxamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psychotropic drugs, cardiac arrhythmia, and sudden death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BmTx3, a scorpion toxin with two putative functional faces separately active on A-type K+ and HERG currents

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Towards a drug concentration effect relationship for QT prolongation and torsades de pointes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged Q-T interval and hypokalemia caused by haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of thioridazine and some of its metabolites to human serum protein and human albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiotoxicity of new antihistamines and cisapride

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of thioridazine and thioridazine metabolites to serum proteins in psychiatric patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of Ito in young and adult human atrial myocytes: evidence for developmental changes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antipsychotic agents and QT changes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac ion channel effects of tolterodine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel method for visualizing nuclear hormone receptor networks relevant to drug metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Problems of heart rate correction in assessment of drug-induced QT interval prolongation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional quantitative structure-activity relationship for inhibition of human ether-a-go-go-related gene potassium channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors influencing phenothiazine-induced ECG changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A family of potassium channel genes related to eag in Drosophila and mammals

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of myocardium to plasma concentration ratios of five antipsychotic drugs: comparison with their ability to induce arrhythmia and sudden death in clinical practice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

QT interval prolongation by non-cardiovascular drugs: issues and solutions for novel drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of drug-induced QT interval prolongation: implications for drug approval and labelling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiological safety of sertindole in dogs with normal and remodeled hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypomagnesaemia in postoperative patients: an important contributing factor in postoperative mortality

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-006-0070-7

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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