(Q40277157)

19 September 2017

title

Dual role of TMS1/ASC in death receptor signaling (English)

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19 September 2017

Parsons MJ

1

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19 September 2017

Vertino PM

series ordinal

2

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19 September 2017

language of work or name

English

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publication date

22 May 2006

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19 September 2017

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19 September 2017

volume

25

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19 September 2017

issue

52

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19 September 2017

page(s)

6948-6958

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209684

19 September 2017

exact match

0 references

cites work

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Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

21 January 2018

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FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

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Methylation silencing of the Apaf-1 gene in acute leukemia

21 January 2018

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Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.

21 January 2018

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ASC/TMS1, a caspase-1 activating adaptor, is downregulated by aberrant methylation in human melanoma

21 January 2018

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Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis

21 January 2018

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ASC-mediated NF-kappaB activation leading to interleukin-8 production requires caspase-8 and is inhibited by CLARP.

21 January 2018

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Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer

21 January 2018

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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Worms gang up on bacteria

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DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

21 January 2018

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Jun kinase phosphorylates and regulates the DNA binding activity of an octamer binding protein, T-cell factor beta1.

21 January 2018

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The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

21 January 2018

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Initial sequencing and analysis of the human genome

21 January 2018

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Effects of methylation on expression of TMS1/ASC in human breast cancer cells

21 January 2018

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An apoptotic signaling pathway in the interferon antiviral response mediated by RNase L and c-Jun NH2-terminal kinase

21 January 2018

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The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase

21 January 2018

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PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B

21 January 2018

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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

21 January 2018

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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

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ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis

21 January 2018

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ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells

21 January 2018

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Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway

21 January 2018

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TMS1/ASC: the cancer connection

21 January 2018

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Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

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Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction

21 January 2018

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Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway

21 January 2018

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ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway

21 January 2018

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Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis

21 January 2018

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Caspase activation: the induced-proximity model

21 January 2018

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Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis.

21 January 2018

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The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest

21 January 2018

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Transcription factor NF-kappaB differentially regulates death receptor 5 expression involving histone deacetylase 1.

21 January 2018

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Caspase activation: revisiting the induced proximity model

21 January 2018

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ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils

21 January 2018

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

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Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

21 January 2018

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The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways

21 January 2018

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Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation

21 January 2018

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Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma

21 January 2018

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Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product

21 January 2018

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Identification of direct genomic targets downstream of the nuclear factor-kappaB transcription factor mediating tumor necrosis factor signaling.

21 January 2018

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

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Aberrant methylation of TMS1 in small cell, non small cell lung cancer and breast cancer

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Tumor necrosis factor signaling.

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1 reference

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PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

21 January 2018

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Transcriptional cross talk between NF-kappaB and p53.

21 January 2018

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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

21 January 2018

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Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer

21 January 2018

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Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

21 January 2018

1 reference

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Identification of NF-kappa B-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference

21 January 2018

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The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

21 January 2018

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7 January 2021

The fundamental role of epigenetic events in cancer

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DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene

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Expression of apoptosis-associated speck-like protein containing a caspase recruitment domain, a pyrin N-terminal homology domain-containing protein, in normal human tissues

1 reference

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Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

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ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules

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Identifiers

DOI

10.1038/SJ.ONC.1209684

1 reference

Dimensions Publication ID

19 September 2017

1050192596

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Fatcat ID

release_gko3jy2yizeijgkk36kb3g25ni

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gko3jy2yizeijgkk36kb3g25ni

24 November 2022

mapped directly with Wikidata item

1 reference