(Q40282751)

19 September 2017

Identifying off-target effects and hidden phenotypes of drugs in human cells (English)

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19 September 2017

11

Stephen W Michnick

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19 September 2017

Marnie L MacDonald

1

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19 September 2017

Jane Lamerdin

2

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19 September 2017

Stephen Owens

3

1 reference

19 September 2017

Brigitte H Keon

4

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19 September 2017

Graham K Bilter

5

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19 September 2017

Zhidi Shang

6

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19 September 2017

Zhengping Huang

7

1 reference

19 September 2017

Helen Yu

8

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19 September 2017

Jennifer Dias

9

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19 September 2017

Tomoe Minami

10

1 reference

19 September 2017

John K Westwick

12

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19 September 2017

7 May 2006

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19 September 2017

Nature Chemical Biology

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19 September 2017

2

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19 September 2017

329-337

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19 September 2017

6

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https://scigraph.springernature.com/pub.10.1038/nchembio790

19 September 2017

0 references

cites work

How molecular profiling could revolutionize drug discovery

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Integrated genomic and proteomic analyses of gene expression in Mammalian cells

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7 January 2021

Microarray reality checks in the context of a complex disease

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7 January 2021

Detection of protein-protein interactions by protein fragment complementation strategies

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7 January 2021

Visualization of biochemical networks in living cells

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7 January 2021

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

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7 January 2021

Measuring drug action in the cellular context using protein-fragment complementation assays

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7 January 2021

A cDNA library functional screening strategy based on fluorescent protein complementation assays to identify novel components of signaling pathways

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3.

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Capturing protein interactions in the secretory pathway of living cells

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Ubiquitin-mediated fluorescence complementation reveals that Jun ubiquitinated by Itch/AIP4 is localized to lysosomes.

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Phosphorylation of beta-arrestin2 regulates its function in internalization of beta(2)-adrenergic receptors

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Post-prenylation-processing enzymes as new targets in oncogenesis

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Cyclin ubiquitination: the destructive end of mitosis

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

The specificities of protein kinase inhibitors: an update

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Clotrimazole inhibits cell proliferation in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Translationally controlled tumor protein is a target of tumor reversion

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7 January 2021

The effects of the Penicillium mycotoxins citrinin, cyclopiazonic acid, ochratoxin A, patulin, penicillic acid, and roquefortine C on in vitro proliferation of porcine lymphocytes

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Mechanism of action of reagents that uncouple oxidative phosphorylation

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https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Patulin-induced cellular toxicity: a vital fluorescence study

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

A potent PPARalpha agonist stimulates mitochondrial fatty acid beta-oxidation in liver and skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

The effect of peroxisome proliferators on mitochondrial bioenergetics.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Reporting the assessment of screening and diagnostic tests.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Detection of TAP family dimerizations by an in vivo assay in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Direct visualization of protein interactions in plant cells

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Amylases in the Human Vagina

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO790

7 January 2021

Identifiers

DOI

10.1038/NCHEMBIO790

1 reference

19 September 2017

1 reference