(Q40304525)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539655%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons (English)

1 reference

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18 January 2020

0 references

3

1 reference

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18 January 2020

6

Mark P Mattson

1 reference

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18 January 2020

5

Vilhelm A Bohr

1 reference

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18 January 2020

author name string

Peisu Zhang

series ordinal

1

1 reference

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18 January 2020

Katsutoshi Furukawa

series ordinal

2

1 reference

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18 January 2020

Xiangru Xu

series ordinal

4

1 reference

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18 January 2020

language of work or name

English

0 references

publication date

15 March 2006

1 reference

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Journal of Neurochemistry

18 January 2020

published in

1 reference

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18 January 2020

volume

97

1 reference

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18 January 2020

issue

2

1 reference

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18 January 2020

page(s)

567-581

1 reference

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A DNA damage checkpoint response in telomere-initiated senescence

18 January 2020

cites work

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Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

21 January 2018

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ATM phosphorylates histone H2AX in response to DNA double-strand breaks

21 January 2018

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Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

21 January 2018

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21 January 2018

Telomeres and telomerase

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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

21 January 2018

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Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain

21 January 2018

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MR evidence of structural and metabolic changes in brains of patients with Werner's syndrome.

21 January 2018

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Nijmegen breakage syndrome: consequences of defective DNA double strand break repair

21 January 2018

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Both estrogen and raloxifene protect against beta-amyloid-induced neurotoxicity in estrogen receptor alpha-transfected PC12 cells by activation of telomerase activity via Akt cascade.

21 January 2018

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p21WAF1 induces permanent growth arrest and enhances differentiation, but does not alter apoptosis in PC12 cells

21 January 2018

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Dual growth arrest pathways in astrocytes and astrocytic tumors in response to Raf-1 activation

21 January 2018

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H2AX: the histone guardian of the genome

21 January 2018

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Recombinant GABA(C) receptors expressed in rat hippocampal neurons after infection with an adenovirus containing the human rho1 subunit

21 January 2018

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DNA polymerase beta interacts with TRF2 and induces telomere dysfunction in a murine mammary cell line

21 January 2018

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The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function.

21 January 2018

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Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.

21 January 2018

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Alteration in calcium channel properties is responsible for the neurotoxic action of a familial frontotemporal dementia tau mutation

21 January 2018

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Mammalian telomeres end in a large duplex loop

21 January 2018

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Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability

21 January 2018

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Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of gamma-H2AX.

21 January 2018

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Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

21 January 2018

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Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity.

21 January 2018

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p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

21 January 2018

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Senescence Induced by Altered Telomere State, Not Telomere Loss

21 January 2018

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The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response

21 January 2018

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Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage.

21 January 2018

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21 January 2018

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Mutant telomere sequences lead to impaired chromosome separation and a unique checkpoint response

21 January 2018

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Telomerase protects developing neurons against DNA damage-induced cell death

21 January 2018

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21 January 2018

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

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Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases

21 January 2018

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Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

21 January 2018

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The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang

21 January 2018

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21 January 2018

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Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity

21 January 2018

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TRF2 Protects Human Telomeres from End-to-End Fusions

21 January 2018

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From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: the telomere loss/DNA damage model of cell aging

21 January 2018

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21 January 2018

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21 January 2018

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Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation

21 January 2018

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Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

21 January 2018

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Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing

21 January 2018

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