(Q40319470)

19 September 2017

Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein (English)

1 reference

19 September 2017

1 reference

Véronique Dorval

1

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PubMed ID

16464864

19 September 2017

Paul E Fraser

series ordinal

2

1 reference

PubMed ID

16464864

19 September 2017

language of work or name

English

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publication date

7 February 2006

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Journal of Biological Chemistry

19 September 2017

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19 September 2017

281

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19 September 2017

9919-9924

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19 September 2017

15

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SUMO protein modification.

19 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Molecular features of human ubiquitin-like SUMO genes and their encoded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Preferential modification of nuclear proteins by a novel ubiquitin-like molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

SUMO-1 modification activates the transcriptional response of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

An E3-like factor that promotes SUMO conjugation to the yeast septins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

The nucleoporin RanBP2 has SUMO1 E3 ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Involvement of PIAS1 in the sumoylation of tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

The polycomb protein Pc2 is a SUMO E3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

SUMO: ligases, isopeptidases and nuclear pores

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Tau paired helical filaments from Alzheimer's disease brain and assembled in vitro are based on beta-structure in the core domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Sepsis inhibits reduction of dehydroascorbic acid and accumulation of ascorbate in astroglial cultures: intracellular ascorbate depletion increases nitric oxide synthase induction and glutamate uptake inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Ubiquitin is a component of paired helical filaments in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Ubiquitination of alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Enhanced SUMOylation in polyglutamine diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

SUMO-1 co-localized with mutant atrophin-1 with expanded polyglutamines accelerates intranuclear aggregation and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

SUMO-1 marks the nuclear inclusions in familial neuronal intranuclear inclusion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

SUMO-1 marks subdomains within glial cytoplasmic inclusions of multiple system atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

SUMOylation of the polyglutamine repeat protein, ataxin-1, is dependent on a functional nuclear localization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

SUMO modification of Huntingtin and Huntington's disease pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Activation of transforming growth factor-beta signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Global analyses of sumoylated proteins in Saccharomyces cerevisiae. Induction of protein sumoylation by cellular stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Sumoylation of Smad4, the Common Smad Mediator of Transforming Growth Factor-β Family Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Global analysis of protein sumoylation in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

In vitro modification of human centromere protein CENP-C fragments by small ubiquitin-like modifier (SUMO) protein: definitive identification of the modification sites by tandem mass spectrometry analysis of the isopeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

A proteomic study of SUMO-2 target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Broad spectrum identification of cellular small ubiquitin-related modifier (SUMO) substrate proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Mutual interactions between the SUMO and ubiquitin systems: a plea of no contest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

The proteasome in brain aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Potential structure/function relationships of predicted secondary structural elements of tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Transcriptional and conformational changes of the tau molecule in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

Tau pathology in Alzheimer disease and other tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

A Proteomic Strategy for Gaining Insights into Protein Sumoylation in Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510127200

21 January 2018

Identifiers

DOI

10.1074/JBC.M510127200

1 reference

19 September 2017

1 reference

PubMed ID

16464864