(Q40327150)

19 September 2017

title

Prediction of anticancer drug potency from expression of genes involved in growth factor signaling (English)

1 reference

19 September 2017

Zunyan Dai

1

1 reference

19 September 2017

Catalin Barbacioru

series ordinal

2

1 reference

19 September 2017

Ying Huang

series ordinal

3

1 reference

19 September 2017

Wolfgang Sadée

series ordinal

4

1 reference

19 September 2017

publication date

26 January 2006

1 reference

19 September 2017

published in

Pharmaceutical Research

1 reference

19 September 2017

volume

23

1 reference

19 September 2017

issue

2

1 reference

19 September 2017

page(s)

336-349

1 reference

Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase

19 September 2017

cites work

1 reference

12 December 2020

New colorimetric cytotoxicity assay for anticancer-drug screening

1 reference

12 December 2020

HER-2-targeted therapy: lessons learned and future directions.

1 reference

12 December 2020

EGFR family signaling and its association with breast cancer development and resistance to chemotherapy (Review).

1 reference

12 December 2020

Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformation

1 reference

12 December 2020

Genomic analysis of metastasis reveals an essential role for RhoC

1 reference

12 December 2020

Cluster analysis and display of genome-wide expression patterns

1 reference

12 December 2020

Growth factor signaling and resistance to cancer chemotherapy

1 reference

12 December 2020

Childhood leukemia--new advances and challenges.

1 reference

12 December 2020

Role of erbB2 in breast cancer chemosensitivity

1 reference

12 December 2020

Targeted cancer therapy

1 reference

12 December 2020

HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.

1 reference

12 December 2020

Neural computing in cancer drug development: predicting mechanism of action

1 reference

12 December 2020

Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart

1 reference

12 December 2020

Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor

1 reference

12 December 2020

An information-intensive approach to the molecular pharmacology of cancer.

1 reference

12 December 2020

ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma

1 reference

12 December 2020

Advances in pharmacogenomics and individualized drug therapy: exciting challenges that lie ahead

1 reference

12 December 2020

Chemosensitivity prediction by transcriptional profiling

1 reference

12 December 2020

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

12 December 2020

Cyr61 expression confers resistance to apoptosis in breast cancer MCF-7 cells by a mechanism of NF-kappaB-dependent XIAP up-regulation

1 reference

12 December 2020

An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines

1 reference

12 December 2020

The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner.

1 reference

12 December 2020

Targeting ErbB receptor signaling: a pan-ErbB approach to cancer

1 reference

12 December 2020

Fibroblast growth factors: an epigenetic mechanism of broad spectrum resistance to anticancer drugs

1 reference

12 December 2020

Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor

1 reference

12 December 2020

Comparing cDNA and oligonucleotide array data: concordance of gene expression across platforms for the NCI-60 cancer cells

1 reference

12 December 2020

Transporter and ion channel gene expression after Caco-2 cell differentiation using 2 different microarray technologies

1 reference

12 December 2020

Modulation of cellular chemoresistance in keratinocytes by activation of different oncogenes

1 reference

12 December 2020

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1 reference

12 December 2020

Cooperative inhibitory effect of ZD1839 (Iressa) in combination with trastuzumab (Herceptin) on human breast cancer cell growth.

1 reference

12 December 2020

Mechanisms of ErbB2-mediated paclitaxel resistance and trastuzumab-mediated paclitaxel sensitization in ErbB2-overexpressing breast cancers

1 reference

12 December 2020

Combination therapy with trastuzumab (Herceptin) and cisplatin for chemoresistant metastatic breast cancer: evidence for receptor-enhanced chemosensitivity

1 reference

12 December 2020

Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance

1 reference

12 December 2020

Identification of novel proteins associated with hepatocellular carcinomas using protein microarrays

1 reference

12 December 2020

Messenger RNA expression of transporter and ion channel genes in undifferentiated and differentiated Caco-2 cells compared to human intestines

1 reference

12 December 2020

Using microarrays to predict resistance to chemotherapy in cancer patients

1 reference

12 December 2020

Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks

1 reference

12 December 2020

Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment

1 reference

12 December 2020

Establishing connections between microarray expression data and chemotherapeutic cancer pharmacology

1 reference

12 December 2020

The angiogenic factor CYR61 in breast cancer: molecular pathology and therapeutic perspectives.

1 reference

12 December 2020

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

1 reference

12 December 2020

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines

1 reference

12 December 2020

Overexpression of the neuropilin 1 (NRP1) gene correlated with poor prognosis in human glioma.

1 reference

12 December 2020

Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer

1 reference

12 December 2020

Activated N-ras contributes to the chemoresistance of human melanoma in severe combined immunodeficiency (SCID) mice by blocking apoptosis

1 reference

12 December 2020

RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival

1 reference

12 December 2020

A gene expression database for the molecular pharmacology of cancer

1 reference

12 December 2020

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

12 December 2020

The role of neuropilin in vascular and tumor biology.

1 reference

12 December 2020

Rationale for combination therapy of chronic myelogenous leukaemia with imatinib and irradiation or alkylating agents: implications for pretransplant conditioning

1 reference

12 December 2020

Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts

1 reference

12 December 2020

TC21 mediates transformation and cell survival via activation of phosphatidylinositol 3-kinase/Akt and NF-kappaB signaling pathway

1 reference

12 December 2020

Evaluation of the clinical significance of HER2 amplification by chromogenic in situ hybridisation in patients with primary breast cancer

1 reference

12 December 2020

Overcoming resistance of cancer cells to apoptosis

1 reference

12 December 2020

Expression and function of CYR61, an angiogenic factor, in breast cancer cell lines and tumor biopsies.

1 reference

12 December 2020

A genome-wide survey of RAS transformation targets

1 reference

12 December 2020

Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin).

1 reference

12 December 2020

Inhibition of epidermal growth factor receptor signaling protects human malignant glioma cells from hypoxia-induced cell death

1 reference

12 December 2020

ADP-ribosylation factor 4 small GTPase mediates epidermal growth factor receptor-dependent phospholipase D2 activation

1 reference

12 December 2020

ZD1839 modulates paclitaxel response in renal cancer by blocking paclitaxel-induced activation of the epidermal growth factor receptor-extracellular signal-regulated kinase pathway

1 reference

12 December 2020

Oncogenomics and the development of new cancer therapies

1 reference

12 December 2020

Gefitinib--a novel targeted approach to treating cancer

1 reference

12 December 2020

Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt

1 reference

12 December 2020

Mining the National Cancer Institute's tumor-screening database: identification of compounds with similar cellular activities

1 reference

12 December 2020

EGF receptor targeting in therapy-resistant human tumors

1 reference

12 December 2020

Activation of phospholipase C induces the expression of the multidrug resistance (MDR1) gene through the Raf-MAPK pathway.

1 reference

12 December 2020

Combinatorial efficacy achieved through two-point blockade within a signaling pathway-a chemical genetic approach.

1 reference

12 December 2020

Transcriptional regulation of the Ras-related protein TC21/R-Ras2 in endothelial cells.

1 reference

12 December 2020

ErbB2 overexpression in an ovarian cancer cell line confers sensitivity to the HSP90 inhibitor geldanamycin

1 reference

12 December 2020

A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

1 reference

12 December 2020

Correlating gene expression with chemical scaffolds of cytotoxic agents: ellipticines as substrates and inhibitors of MDR1.

1 reference

12 December 2020

ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy.

1 reference

12 December 2020

The EGF/ErbB receptor family and apoptosis

1 reference

12 December 2020

Betaglycan presents ligand to the TGF beta signaling receptor.

1 reference

12 December 2020

10.1007/S11095-005-9260-Y

Identifiers

DOI

1 reference

19 September 2017

1 reference