(Q28215324)

Related RAS viral (r-ras) oncogene 2

GOA release 2020-03-11

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GOA release 2020-03-11

8

Channing J Der

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author name string

Gretchen A Murphy

1

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Suzanne M Graham

2

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Staeci Morita

3

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Sarah E Reks

4

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Kelley Rogers-Graham

5

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Anne Vojtek

6

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Grant G Kelley

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

22 March 2002

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published in

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volume

277

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issue

12

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page(s)

9966-75

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cites work

The GTPase superfamily: a conserved switch for diverse cell functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Proteins regulating Ras and its relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

The Ras branch of small GTPases: Ras family members don't fall far from the tree

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

TC21 causes transformation by Raf-independent signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

TC21 and Ras share indistinguishable transforming and differentiating activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

A human oncogene of the RAS superfamily unmasked by expression cDNA cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Integrin activation by R-ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

p120 GAP modulates Ras activation of Jun kinases and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Transformation of intestinal epithelial cells by chronic TGF-beta1 treatment results in downregulation of the type II TGF-beta receptor and induction of cyclooxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Signal transduction elements of TC21, an oncogenic member of the R-Ras subfamily of GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

R-Ras is regulated by activators and effectors distinct from those that control Ras function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

The complexity of Raf-1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Understanding Ras: 'it ain't over 'til it's over'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Evidence for a Ras/Ral signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Ras caught in another affair: the exchange factors for Ral.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Ras regulation. NF is enough of GAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Identification of AF-6 and canoe as putative targets for Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Phospholipase C(epsilon): a novel Ras effector

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

The effector interactions of p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Multiple Ras functions can contribute to mammalian cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Signal pathways which promote invasion and metastasis: critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Analyses of TC21/R-Ras2 signaling and biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Construction and applications of a highly transmissible murine retrovirus shuttle vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Functional analysis of a growth factor-responsive transcription factor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Ras-mediated transcription activation: analysis by transient cotransfection assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Biological assays for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

A T42A Ran mutation: differential interactions with effectors and regulators, and defect in nuclear protein import

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Spatial sensing in fibroblasts mediated by 3' phosphoinositides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Protein binding and signaling properties of RIN1 suggest a unique effector function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Characterization of a natural inhibitor of the insulin receptor tyrosine kinase: cDNA cloning, purification, and anti-mitogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Regulation of the insulin signalling pathway by cellular protein-tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Solution structure of the Ras-binding domain of RGL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Phospholipase D stimulation by receptor tyrosine kinases mediated by protein kinase C and a Ras/Ral signaling cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Plasma membrane recruitment of RalGDS is critical for Ras-dependent Ral activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Mechanism of activation and function of protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Activation of the Ral and phosphatidylinositol 3' kinase signaling pathways by the ras-related protein TC21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Induction of postmitotic neuroretina cell proliferation by distinct Ras downstream signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

The rat protein encoded by clone pp63 is a fetuinα2-HS glycoprotein-like molecule, but is it the tyrosine kinase inhibitor pp63?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Transformation of mammalian cells by constitutively active MAP kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Structural and biochemical analysis of Ras-effector signaling via RalGDS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

Mammalian expression vectors for Ras family proteins: generation and use of expression constructs to analyze Ras family function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200

PI-3-kinase is an essential anti-apoptotic effector in the proliferative response of primary human epithelial cells to mutant RAS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109059200