(Q42835042)

8 November 2017

Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways (English)

1 reference

8 November 2017

Rusyn EV

1

1 reference

8 November 2017

Reynolds ER

2

1 reference

8 November 2017

Shao H

3

1 reference

8 November 2017

Grana TM

4

1 reference

8 November 2017

Chan TO

5

1 reference

8 November 2017

Andres DA

6

1 reference

8 November 2017

Cox AD

7

1 reference

8 November 2017

language of work or name

English

0 references

publication date

1 September 2000

1 reference

8 November 2017

1 reference

8 November 2017

19

1 reference

8 November 2017

4685-4694

1 reference

8 November 2017

41

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203836

8 November 2017

0 references

cites work

Increasing complexity of Ras signaling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Construction and applications of a highly transmissible murine retrovirus shuttle vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

The small GTPase Cdc42 initiates an apoptotic signaling pathway in Jurkat T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Biological assays for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Biological assays for cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Protein prenylation: more than just glue?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Analysis of Ras protein expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Transcriptional regulation by MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Cell cycle: routine role for Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

TC21 causes transformation by Raf-independent signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Ras-mediated transcription activation: analysis by transient cotransfection assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

R-Ras is regulated by activators and effectors distinct from those that control Ras function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

R-Ras signals through specific integrin alpha cytoplasmic domains to promote migration and invasion of breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

The activation of phosphatidylinositol 3-kinase by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

How do small GTPase signal transduction pathways regulate cell cycle entry?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Muscarinic receptors transform NIH 3T3 cells through a Ras-dependent signalling pathway inhibited by the Ras-GTPase-activating protein SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Characterization of Ral GDP dissociation stimulator-like (RGL) activities to regulate c-fos promoter and the GDP/GTP exchange of Ral.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Synergistic activation of c-fos promoter activity by Raf and Ral GDP dissociation stimulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Differential roles of Akt, Rac, and Ral in R-Ras-mediated cellular transformation, adhesion, and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

An essential role for Rac in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

A role for Rho in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

The Ras branch of small GTPases: Ras family members don't fall far from the tree

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Biochemical characterization of the Ras-related GTPases Rit and Rin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Farnesyltransferase inhibitors induce cytochrome c release and caspase 3 activation preferentially in transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Signaling pathways in Ras-mediated tumorigenicity and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Stimulation of gene induction and cell growth by the Ras effector Rlf

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Integrin activation by R-ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

Effector domain mutants of Rho dissociate cytoskeletal changes from nuclear signaling and cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

7 January 2021

Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

7 January 2021

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

7 January 2021

Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

7 January 2021

Farnesyltransferase inhibitors: targeting the molecular basis of cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

7 January 2021

DsbG, a protein disulfide isomerase with chaperone activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203836

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203836

1 reference

Dimensions Publication ID

8 November 2017

0 references

1 reference