(Q40339485)

English

A novel and cytogenetically cryptic t(7;21)(p22;q22) in acute myeloid leukemia results in fusion of RUNX1 with the ubiquitin-specific protease gene USP42.

scientific article published on February 2006

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Europe PubMed Central

PubMed publication ID

19 September 2017

A novel and cytogenetically cryptic t(7;21)(p22;q22) in acute myeloid leukemia results in fusion of RUNX1 with the ubiquitin-specific protease gene USP42. (English)

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Europe PubMed Central

PubMed publication ID

19 September 2017

acute myeloid leukemia

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K Paulsson

1

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Ioannis Panagopoulos

object named as

I Panagopoulos

6

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5

object named as

B Johansson

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Europe PubMed Central

PubMed publication ID

19 September 2017

author name string

A N Békássy

2

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Europe PubMed Central

PubMed publication ID

19 September 2017

T Olofsson

3

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Europe PubMed Central

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19 September 2017

F Mitelman

4

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Europe PubMed Central

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19 September 2017

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publication date

1 February 2006

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Europe PubMed Central

PubMed publication ID

19 September 2017

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Europe PubMed Central

PubMed publication ID

19 September 2017

20

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Europe PubMed Central

PubMed publication ID

19 September 2017

2

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Europe PubMed Central

PubMed publication ID

19 September 2017

224-229

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Chromosome translocations: dangerous liaisons revisited.

1 reference

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Clinical and biological importance of cytogenetic abnormalities in childhood and adult acute lymphoblastic leukemia

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The FIP1L1-PDGFRalpha fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: implications for diagnosis, classification, and management.

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21 January 2018

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

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Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia

1 reference

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Role of AML1/Runx1 in the pathogenesis of hematological malignancies

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Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

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Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

1 reference

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A novel gene, FGA7, is fused to RUNX1/AML1 in a t(4;21)(q28;q22) in a patient with T-cell acute lymphoblastic leukemia

1 reference

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21 January 2018

Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations

1 reference

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PRDX4, a member of the peroxiredoxin family, is fused to AML1 (RUNX1) in an acute myeloid leukemia patient with a t(X;21)(p22;q22).

1 reference

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21 January 2018

AML1-FOG2 fusion protein in myelodysplasia

1 reference

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21 January 2018

Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases

1 reference

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Treatment stratification based on initial in vivo response in acute myeloid leukaemia in children without Down's syndrome: results of NOPHO-AML trials

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New strategy for multi-colour fluorescence in situ hybridisation: COBRA: COmbined Binary RAtio labelling

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Human chromosome 7 circa 2004: a model for structural and functional studies of the human genome

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t(7;12)(q36;p13) and t(7;12)(q32;p13)--translocations involving ETV6 in children 18 months of age or younger with myeloid disorders

1 reference

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21 January 2018

A 76-kb duplicon maps close to the BCR gene on chromosome 22 and the ABL gene on chromosome 9: possible involvement in the genesis of the Philadelphia chromosome translocation

1 reference

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21 January 2018

The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer

1 reference

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21 January 2018

A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation

1 reference

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21 January 2018

Aneurysmal bone cyst variant translocations upregulate USP6 transcription by promoter swapping with the ZNF9, COL1A1, TRAP150, and OMD genes

1 reference

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21 January 2018

Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation

1 reference

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21 January 2018

Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia

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Identification of CBL, a proto‐oncogene at 11q23.3, as a novel MLL fusion partner in a patient with de novo acute myeloid leukemia

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21 January 2018

A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia.

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21 January 2018

Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia

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Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis

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Primary vs. secondary neoplasia-associated chromosomal abnormalities--balanced rearrangements vs. genomic imbalances?

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7 January 2021

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10.1038/SJ.LEU.2404076

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Europe PubMed Central

PubMed publication ID

19 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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