(Q40343195)

English

Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, I kappa B kinase activation and NF-kappa B-regulated gene expression

scientific article published on March 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, I kappa B kinase activation and NF-kappa B-regulated gene expression (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

1 reference

based on heuristic

inferred from title

author name string

Shishodia S

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Aggarwal BB

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

language of work or name

0 references

publication date

1 March 2006

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

25

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

1463-1473

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

NF-kappaB and bone: the breaking point

1 reference

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Signalling pathways of the TNF superfamily: a double-edged sword

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Nuclear factor-kappaB: the enemy within

1 reference

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Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin

1 reference

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Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

1 reference

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Evidence that receptor activator of nuclear factor (NF)-kappaB ligand can suppress cell proliferation and induce apoptosis through activation of a NF-kappaB-independent and TRAF6-dependent mechanism

1 reference

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Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells.

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A new indian source of diosgenin (Costus speciosus)

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Drugs from Third World plants: the future

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Protein kinase C-zeta regulates transcription of the matrix metalloproteinase-9 gene induced by IL-1 and TNF-alpha in glioma cells via NF-kappa B

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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ICU management of severe malaria

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Diosgenin and beta-sitosterol: isolation from solanum xanthocarpum tissue cultures

1 reference

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Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression

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Role of collagenases in tumor cell invasion

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Diosgenin induces cell cycle arrest and apoptosis in human leukemia K562 cells with the disruption of Ca2+ homeostasis

1 reference

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Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

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Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B

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A plant steroid, diosgenin, induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells

1 reference

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Changes in lipoxygenase activities in human erythroleukemia (HEL) cells during diosgenin-induced differentiation

1 reference

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Differential IκB Kinase Activation and IκBα Degradation by Interleukin-1β and Tumor Necrosis Factor-α in Human U937 Monocytic Cells

1 reference

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7 January 2021

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Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3.

1 reference

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7 January 2021

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

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7 January 2021

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Gastroprotective effect of fenugreek seeds (Trigonella foenum graecum) on experimental gastric ulcer in rats

1 reference

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Diosgenin and yamogenin levels in some Indian plant samples

1 reference

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Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek

1 reference

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7 January 2021

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Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis

1 reference

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Nuclear factor-kappaB: a friend or a foe in cancer?

1 reference

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p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy

1 reference

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Hypocholesterolaemic effect of fenugreek seeds in dogs

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

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7 January 2021

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

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7 January 2021

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Diosgenin-3-O-alpha-L-rhamnopyranosyl-(1 --> 4)-beta-D-glucopyranoside obtained as a new anticancer agent from Dioscorea futschauensis induces apoptosis on human colon carcinoma HCT-15 cells via mitochondria-controlled apoptotic pathway

1 reference

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Dietary diosgenin attenuates subacute intestinal inflammation associated with indomethacin in rats

1 reference

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Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells

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In vivo antiosteoporotic activity of a fraction of Dioscorea spongiosa and its constituent, 22-O-methylprotodioscin

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Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

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Diosgenin, a Steroid Saponin of Trigonella foenum graecum (Fenugreek), Inhibits Azoxymethane-Induced Aberrant Crypt Foci Formation in F344 Rats and Induces Apoptosis in HT-29 Human Colon Cancer Cells

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.1158/1055-9965.1392.13.8

Identifiers

10.1038/SJ.ONC.1209194

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

ResearchGate publication ID

0 references

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