(Q40343692)

19 September 2017

title

Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B. (English)

1 reference

19 September 2017

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5

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11 June 2020

Paola Fisicaro

1

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11 June 2020

Valeria Barili

2

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11 June 2020

Barbara Montanini

3

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11 June 2020

Francesca Guerrieri

6

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11 June 2020

Pietro Lampertico

13

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11 June 2020

Gabriele Missale

14

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11 June 2020

Massimo Levrero

15

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11 June 2020

Carlo Ferrari

17

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11 June 2020

9

Marco Massari

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11 June 2020

7

Debora Salerno

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11 June 2020

10

M Cristina Cavallo

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11 June 2020

12

Tiziana Giuberti

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11 June 2020

16

Simone Ottonello

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11 June 2020

author name string

Greta Acerbi

4

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11 June 2020

Carolina Boni

8

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11 June 2020

Glenda Grossi

11

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11 June 2020

language of work or name

English

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publication date

6 February 2017

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19 September 2017

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11 June 2020

volume

23

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11 June 2020

issue

3

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11 June 2020

page(s)

327-336

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EASL clinical practice guidelines: Management of chronic hepatitis B virus infection

11 June 2020

cites work

1 reference

Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection

21 January 2018

1 reference

Immunology of hepatitis B virus and hepatitis C virus infection

21 January 2018

1 reference

Restoring function in exhausted CD8 T cells during chronic viral infection

21 January 2018

1 reference

Inhibitory receptors on lymphocytes: insights from infections

21 January 2018

1 reference

Regulatory T cells and viral liver disease

21 January 2018

1 reference

Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection

21 January 2018

1 reference

Role of regulatory T cells during virus infection

21 January 2018

1 reference

Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation

21 January 2018

1 reference

Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection

21 January 2018

1 reference

Combined blockade of programmed death-1 and activation of CD137 increase responses of human liver T cells against HBV, but not HCV.

21 January 2018

1 reference

Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection.

21 January 2018

1 reference

The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function

21 January 2018

1 reference

Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection

21 January 2018

1 reference

Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation

21 January 2018

1 reference

Enhanced expression of cell cycle regulatory genes in virus-specific memory CD8+ T cells

21 January 2018

1 reference

Memory CD8 T-cell differentiation during viral infection

21 January 2018

1 reference

The dual immunoregulatory roles of stress proteins.

21 January 2018

1 reference

A novel role for Hedgehog in T-cell receptor signaling: implications for development and immunity.

21 January 2018

1 reference

HSP70 mediates degradation of the p65 subunit of nuclear factor κB to inhibit inflammatory signaling

21 January 2018

1 reference

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

1 reference

Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy

21 January 2018

1 reference

Proteasome activation: An innovative promising approach for delaying aging and retarding age-related diseases.

21 January 2018

1 reference

ATM function and telomere stability

21 January 2018

1 reference

DNA damage checkpoints in stem cells, ageing and cancer.

21 January 2018

1 reference

Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

21 January 2018

1 reference

T cell metabolism drives immunity

21 January 2018

1 reference

Proteasomes in immune cells: more than peptide producers?

21 January 2018

1 reference

Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties

21 January 2018

1 reference

Selective targeting of synthetic antioxidants to mitochondria: towards a mitochondrial medicine for neurodegenerative diseases?

21 January 2018

1 reference

Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expression

21 January 2018

1 reference

Functional signatures of protective antiviral T-cell immunity in human virus infections.

21 January 2018

1 reference

Mitochondria: more than just a powerhouse

21 January 2018

1 reference

21 January 2018

1 reference

T cell antigen receptor activation and actin cytoskeleton remodeling

21 January 2018

1 reference

Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

21 January 2018

1 reference

Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.

21 January 2018

1 reference

Molecular and functional profiling of memory CD8 T cell differentiation.

21 January 2018

1 reference

Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion

21 January 2018

1 reference

Increased mitochondrial mass characterizes the survival defect of HIV-specific CD8(+) T cells

21 January 2018

1 reference

21 January 2018

The hallmarks of aging

1 reference

Aging and immune function: molecular mechanisms to interventions

21 January 2018

1 reference

Mitochondrial metabolism in T cell activation and senescence: a mini-review

21 January 2018

1 reference

The immune system in extreme longevity

21 January 2018

1 reference

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres

21 January 2018

1 reference

DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway

21 January 2018

1 reference

Autophagy and the immune function in aging

21 January 2018

1 reference

Control of mitochondrial integrity in ageing and disease

21 January 2018

1 reference

Impaired quality control of mitochondria: aging from a new perspective.

21 January 2018

1 reference

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

21 January 2018

1 reference

Distinct Metabolic Requirements of Exhausted and Functional Virus-Specific CD8 T Cells in the Same Host.

21 January 2018

1 reference

The Immune-Metabolic Basis of Effector Memory CD4+ T Cell Function under Hypoxic Conditions

21 January 2018

1 reference

Convergence of multiple signaling pathways is required to coordinately up-regulate mtDNA and mitochondrial biogenesis during T cell activation

21 January 2018

1 reference

Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development

21 January 2018

1 reference

Electron transport complex I is required for CD8+ T cell function.

21 January 2018

1 reference

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming.

21 January 2018

1 reference

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

21 January 2018

1 reference

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

21 January 2018

1 reference

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

21 January 2018

1 reference

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

21 January 2018

1 reference

A travel guide to Cytoscape plugins

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NM.4275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28165481%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference