(Q53354360)

13 May 2018

review article

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title

Proteasomes in immune cells: more than peptide producers? (English)

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13 May 2018

author

Michael Basler

series ordinal

3

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13 May 2018

author name string

Marcus Groettrup

series ordinal

1

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13 May 2018

Christopher J Kirk

series ordinal

2

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13 May 2018

publication date

11 December 2009

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13 May 2018

Nature Reviews Immunology

published in

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13 May 2018

volume

10

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13 May 2018

issue

1

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13 May 2018

page(s)

73-78

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13 May 2018

Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens

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The final touches make perfect the peptide-MHC class I repertoire

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A role for the proteasome regulator PA28alpha in antigen presentation

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Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28

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Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands

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31 March 2020

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Structural and serological similarity of MHC-linked LMP and proteasome (multicatalytic proteinase) complexes

31 March 2020

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31 March 2020

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A third interferon-gamma-induced subunit exchange in the 20S proteasome.

31 March 2020

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Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma

31 March 2020

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cDNA cloning and interferon gamma down-regulation of proteasomal subunits X and Y

31 March 2020

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Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes

31 March 2020

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Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver

31 March 2020

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Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection

31 March 2020

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Antigen processing by the proteasome

31 March 2020

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Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

31 March 2020

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MHC-linked LMP gene products specifically alter peptidase activities of the proteasome

31 March 2020

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Incorporation of major histocompatibility complex – encoded subunits LMP2 and LMP7 changes the quality of the 20S proteasome polypeptide processing products independent of interferon‐γ

31 March 2020

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Structure of 20S proteasome from yeast at 2.4 A resolution

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The structure of the mammalian 20S proteasome at 2.75 A resolution

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Altered peptidase and viral-specific T cell response in LMP2 mutant mice.

31 March 2020

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MHC class I expression in mice lacking the proteasome subunit LMP-7

31 March 2020

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Regulation of CD8+ T cell development by thymus-specific proteasomes

31 March 2020

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Immunoproteasomes down-regulate presentation of a subdominant T cell epitope from lymphocytic choriomeningitis virus

31 March 2020

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Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens.

31 March 2020

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Immunoproteasome-deficient mice mount largely normal CD8+ T cell responses to lymphocytic choriomeningitis virus infection and DNA vaccination

31 March 2020

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Immunoproteasomes are essential for clearance of Listeria monocytogenes in nonlymphoid tissues but not for induction of bacteria-specific CD8+ T cells

31 March 2020

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Cellular responses to interferon-gamma

31 March 2020

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An altered T cell repertoire in MECL-1-deficient mice

31 March 2020

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T cells lacking immunoproteasome subunits MECL-1 and LMP7 hyperproliferate in response to polyclonal mitogens

31 March 2020

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The proteasome immunosubunit multicatalytic endopeptidase complex-like 1 is a T-cell-intrinsic factor influencing homeostatic expansion

31 March 2020

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Expression of housekeeping and immunoproteasome subunit genes is differentially regulated in positively and negatively selecting thymic stroma subsets

31 March 2020

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Proteasomes shape the repertoire of T cells participating in antigen-specific immune responses.

31 March 2020

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Exclusive expression of proteasome subunit {beta}5t in the human thymic cortex.

31 March 2020

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Thymoproteasome: probable role in generating positively selecting peptides

31 March 2020

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The repertoire of T cells shaped by a single MHC/peptide ligand.

31 March 2020

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Immunoproteasome subunit deficiencies impact differentially on two immunodominant influenza virus-specific CD8+ T cell responses

31 March 2020

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Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products

31 March 2020

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

31 March 2020

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A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis.

31 March 2020

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Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

31 March 2020

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The biological functions of T helper 17 cell effector cytokines in inflammation

31 March 2020

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Dextran sulfate sodium-induced colitis is associated with enhanced low molecular mass polypeptide 2 (LMP2) expression and is attenuated in LMP2 knockout mice

31 March 2020

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Structural plasticity of the proteasome and its function in antigen processing.

31 March 2020

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12 December 2020

Critical role for the immunoproteasome subunit LMP7 in the resistance of mice to Toxoplasma gondii infection

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12 December 2020

Development of proteasome inhibitors in oncology and autoimmune diseases.

1 reference

12 December 2020

Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain)

1 reference

12 December 2020

Identification of MECL-1 (LMP-10) as the third IFN-gamma-inducible proteasome subunit

1 reference

12 December 2020

Purification of an 11 S regulator of the multicatalytic protease

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12 December 2020

Identifiers

DOI

10.1038/NRI2687

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13 May 2018

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13 May 2018