(Q40352532)

19 September 2017

title

Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1. (English)

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19 September 2017

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acute myeloid leukemia

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Bonhoure E

1

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19 September 2017

Pchejetski D

2

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19 September 2017

Aouali N

3

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19 September 2017

Morjani H

4

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19 September 2017

Levade T

5

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19 September 2017

Kohama T

6

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19 September 2017

Cuvillier O

7

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19 September 2017

publication date

1 January 2006

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19 September 2017

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19 September 2017

volume

20

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19 September 2017

issue

1

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19 September 2017

page(s)

95-102

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2404023

19 September 2017

exact match

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cites work

Biologically active sphingolipids in cancer pathogenesis and treatment

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction.

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Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy

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Sphingosine in apoptosis signaling

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Sphingosine-1-phosphate: an enigmatic signalling lipid

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Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

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Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells

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Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells

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7 January 2021

Sphingosine kinase activity counteracts ceramide-mediated cell death in human melanoma cells: role of Bcl-2 expression

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404023

7 January 2021

Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria

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7 January 2021

An oncogenic role of sphingosine kinase

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Lack of ceramide generation in TF-1 human myeloid leukemic cells resistant to ionizing radiation

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7 January 2021

Multidrug resistance in haematological malignancies.

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7 January 2021

Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404023

7 January 2021

Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404023

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Molecular cloning and functional characterization of murine sphingosine kinase

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7 January 2021

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

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7 January 2021

Quantitative determination of ceramide using diglyceride kinase

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7 January 2021

Enzymatic measurement of sphingosine 1-phosphate

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7 January 2021

Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant

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7 January 2021

beta(2)-microglobulin induces apoptosis in HL-60 human leukemia cell line and its multidrug resistant variants overexpressing MRP1 but lacking Bax or overexpressing P-glycoprotein

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Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.

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7 January 2021

F-12509A, a new sphingosine kinase inhibitor, produced by a discomycete

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Inhibition of recombinant sphingosine kinases by novel inhibitors of microbial origin, F-12509A and B-5354c.

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7 January 2021

IAP family proteins--suppressors of apoptosis

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7 January 2021

The involvement of sphingolipids in multidrug resistance

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7 January 2021

P-glycoprotein in acute myeloid leukaemia: therapeutic implications of its association with both a multidrug-resistant and an apoptosis-resistant phenotype

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7 January 2021

A novel enzyme that catalyzes the esterification of N-acetylsphingosine. Metabolism of C2-ceramides

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7 January 2021

The therapeutic potential of modulating the ceramide/sphingomyelin pathway

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7 January 2021

Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities

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7 January 2021

Protein kinase C and platelet inhibition by D-erythro-sphingosine: comparison with N,N-dimethylsphingosine and commercial preparation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404023

7 January 2021

The signal modulator protein 14-3-3 is a target of sphingosine- or N,N-dimethylsphingosine-dependent kinase in 3T3(A31) cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404023

7 January 2021

Characterization of cytotoxicity induced by sphingolipids in multidrug-resistant leukemia cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404023

7 January 2021

Effective cytotoxicity against human leukemias and chemotherapy-resistant leukemia cell lines by N-N-dimethylsphingosine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404023

7 January 2021

Sphingosine kinase inhibitors in the apoptosis of leukaemia cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404023

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2404023

1 reference

Dimensions Publication ID

19 September 2017

1006587100

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1 reference