(Q45215121)

10 December 2017

Sphingosine kinase activity counteracts ceramide-mediated cell death in human melanoma cells: role of Bcl-2 expression (English)

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10 December 2017

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5

Sarah Spiegel

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10 December 2017

Meryem Bektas

1

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10 December 2017

Puneet S Jolly

2

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10 December 2017

Carola Müller

3

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10 December 2017

Jürgen Eberle

4

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10 December 2017

Christoph C Geilen

6

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10 December 2017

language of work or name

English

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publication date

1 January 2005

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10 December 2017

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10 December 2017

24

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10 December 2017

178-187

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10 December 2017

1

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208019

10 December 2017

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cites work

Decreased proliferation of human melanoma cell lines caused by antisense RNA against translation factor eIF-4A1.

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Sphingolipid signaling in epidermal homeostasis. Current knowledge and new therapeutic approaches in dermatology

21 January 2018

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Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Ceramide: role in growth inhibitory cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-alpha-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line. Role for endogenous ceramide in mediating the action of exogenous ceramide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Sphingosine kinase type 1 induces G12/13-mediated stress fiber formation, yet promotes growth and survival independent of G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Overexpression of acid ceramidase protects from tumor necrosis factor-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Ceramide-induced cell death in primary neuronal cultures: upregulation of ceramide levels during neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Induction of ceramide-mediated apoptosis by the anticancer phospholipid analog, hexadecylphosphocholine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Bcl-2 interrupts the ceramide-mediated pathway of cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

Ceramide-mediated clustering is required for CD95-DISC formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

Platelet-derived growth factor-induced activation of sphingosine kinase requires phosphorylation of the PDGF receptor tyrosine residue responsible for binding of PLCgamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

The CD95(APO-1/Fas) DISC and beyond

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

bcl-2 over-expression enhances NF-kappaB activity and induces mmp-9 transcription in human MCF7(ADR) breast-cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208019

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208019

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Dimensions Publication ID

10 December 2017

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1 reference