(Q40354805)

19 September 2017

title

A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids (English)

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19 September 2017

6

Aldons J Lusis

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19 September 2017

Diana M Shih

1

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19 September 2017

Heidi R Kast-Woelbern

2

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19 September 2017

Jack Wong

3

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19 September 2017

Yu-Rong Xia

4

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19 September 2017

Peter A Edwards

5

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19 September 2017

publication date

3 November 2005

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Journal of Lipid Research

19 September 2017

published in

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19 September 2017

volume

47

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19 September 2017

issue

2

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19 September 2017

page(s)

384-392

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Serum esterases. II. An enzyme hydrolysing diethyl p-nitrophenyl phosphate (E600) and its identity with the A-esterase of mammalian sera

19 September 2017

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Serum paraoxonase status: a major factor in determining resistance to organophosphates.

21 January 2018

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Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3.

21 January 2018

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Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase

21 January 2018

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Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein

21 January 2018

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Paraoxonase (PON1) phenotype is a better predictor of vascular disease than is PON1(192) or PON1(55) genotype.

21 January 2018

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Paraoxonase status in coronary heart disease: are activity and concentration more important than genotype?

21 January 2018

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Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

21 January 2018

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Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis

21 January 2018

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Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice

21 January 2018

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Genetic and environmental factors modulating serum concentrations and activities of the antioxidant enzyme paraoxonase-1

21 January 2018

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Replacement of dietary saturated fat with trans fat reduces serum paraoxonase activity in healthy men and women

21 January 2018

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Smoking is associated with reduced serum paraoxonase activity and concentration in patients with coronary artery disease.

21 January 2018

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Serum paraoxonase is reduced in type 1 diabetic patients compared to non-diabetic, first degree relatives; influence on the ability of HDL to protect LDL from oxidation

21 January 2018

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Oxidized phospholipids induce changes in hepatic paraoxonase and ApoJ but not monocyte chemoattractant protein-1 via interleukin-6.

21 January 2018

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Daily moderate alcohol consumption increases serum paraoxonase activity; a diet-controlled, randomised intervention study in middle-aged men.

21 January 2018

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Light, but not heavy alcohol drinking, stimulates paraoxonase by upregulating liver mRNA in rats and humans

21 January 2018

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Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation

21 January 2018

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Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins

21 January 2018

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Simvastatin modulates expression of the PON1 gene and increases serum paraoxonase: a role for sterol regulatory element-binding protein-2.

21 January 2018

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Dietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism

21 January 2018

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Induction of the paraoxonase-1 gene expression by resveratrol

21 January 2018

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Identification of a nuclear receptor for bile acids

21 January 2018

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Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

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Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

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Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR

21 January 2018

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Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

21 January 2018

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FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4

21 January 2018

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Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4

21 January 2018

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Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids

21 January 2018

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Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway

21 January 2018

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The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by

21 January 2018

1 reference

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Genetic-dietary regulation of serum paraoxonase expression and its role in atherogenesis in a mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500378-JLR200

Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation

21 January 2018

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Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

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Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine

21 January 2018

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Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors

21 January 2018

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Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA.

21 January 2018

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Mouse FGF15 is the ortholog of human and chick FGF19, but is not uniquely required for otic induction.

21 January 2018

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Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

21 January 2018

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Control of pancreas and liver gene expression by HNF transcription factors

21 January 2018

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Sterol regulatory element-binding protein-2 interacts with hepatocyte nuclear factor-4 to enhance sterol isomerase gene expression in hepatocytes

21 January 2018

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The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

21 January 2018

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Proinflammatory Cytokines But Not Acute Phase Serum Amyloid A Or C-Reactive Protein, Downregulate Paraoxonase 1 (Pon1) Expression By Hepg2 Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500378-JLR200

10.1194/JLR.M500378-JLR200

21 January 2018

Identifiers

DOI

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19 September 2017

1 reference