(Q40371734)

19 September 2017

Resensitization of breast cancer cells to anoikis by tropomyosin-1: role of Rho kinase-dependent cytoskeleton and adhesion (English)

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19 September 2017

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Shantaram Bharadwaj

1

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19 September 2017

Ruchi Thanawala

2

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19 September 2017

Giulia Bon

3

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19 September 2017

Rita Falcioni

4

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19 September 2017

G L Prasad

5

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19 September 2017

language of work or name

English

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publication date

1 December 2005

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19 September 2017

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19 September 2017

24

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19 September 2017

8291-8303

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19 September 2017

56

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208993

19 September 2017

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cites work

Matrix attachment regulates Fas-induced apoptosis in endothelial cells: a role for c-flip and implications for anoikis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Regulation of nucleocytoplasmic trafficking by cell adhesion receptors and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

N terminus is essential for tropomyosin functions: N-terminal modification disrupts stress fiber organization and abolishes anti-oncogenic effects of tropomyosin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Putting tumours in context

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Biochemical pathways of caspase activation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Rac1 protects epithelial cells against anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Integrin signaling to the actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Integrin signalling during tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Switch from alphavbeta5 to alphavbeta6 integrin expression protects squamous cell carcinomas from anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Polycystin-2 associates with tropomyosin-1, an actin microfilament component

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Suppression of the transformed phenotype of breast cancer by tropomyosin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Alpha 3 beta 1 integrin promotes keratinocyte cell survival through activation of a MEK/ERK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Alpha 4 integrin increases anoikis of human osteosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Regulation of Bcl-2 proteins during anoikis and amorphosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

The alpha 6 beta 4 integrin and epithelial cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Cripto-1 overexpression leads to enhanced invasiveness and resistance to anoikis in human MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Sequence and tissue distribution of the integrin alpha 9 subunit, a novel partner of beta 1 that is widely distributed in epithelia and muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Cytoskeletal changes in cell transformation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha(5)beta(1) fibronectin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Expression of transduced tropomyosin 1 cDNA suppresses neoplastic growth of cells transformed by the ras oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

A cDNA encoding a muscle-type tropomyosin cloned from a human epithelial cell line: identity with human fibroblast tropomyosin TM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

p16(MTS-1/CDKN2/INK4a) in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Transforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Bidirectional signaling between the cytoskeleton and integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Get a ligand, get a life: integrins, signaling and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Spatial and temporal changes in Bax subcellular localization during anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Inhibition of c-Abl tyrosine kinase activity by filamentous actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

ADF/cofilin and actin dynamics in disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

In an adhesion dependent human gastric adenocarcinoma cell line, integrin ligation without adhesion rescues from anoikis but is not sufficient for cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Regulation of anoikis by Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Tumour-stromal interactions. Integrins and cell adhesions as modulators of mammary cell survival and transformation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Hypoxia-induced vascular endothelial growth factor transcription and protection from apoptosis are dependent on alpha6beta1 integrin in breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Increased Bcl-xL expression mediates v-Src-induced resistance to anoikis in intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Actin dynamics: tropomyosin provides stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Focal adhesions - the cytoskeletal connection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Actin binding proteins: regulation of cytoskeletal microfilaments

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Host microenvironment in breast cancer development: epithelial-cell-stromal-cell interactions and steroid hormone action in normal and cancerous mammary gland

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

The collagen receptor integrins have distinct ligand recognition and signaling functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Possible involvement of the inactivation of the Rho-Rho-kinase pathway in oncogenic Ras-induced transformation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Integrin alphavbeta3 promotes anchorage-dependent apoptosis in human intestinal carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Tropomyosin isoforms in nonmuscle cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Expression and ligand binding of alpha 2 beta 1 integrin on breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Structural interactions between actin, tropomyosin, caldesmon and calcium binding protein and the regulation of smooth muscle thin filaments.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Human MCF10A mammary epithelial cells undergo apoptosis following actin depolymerization that is independent of attachment and rescued by Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Use and properties of ROCK-specific inhibitor Y-27632.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Activated Src increases adhesion, survival and alpha2-integrin expression in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Alterations in tropomyosin isoform expression in human transitional cell carcinoma of the urinary bladder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Suppression of src-induced transformed phenotype by expression of tropomyosin-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis, in primary breast tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Analysis of the transcriptional program induced by Raf in epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Integrins, oncogenes, and anchorage independence.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Cytoskeletal organization in tropomyosin-mediated reversion of ras-transformation: Evidence for Rho kinase pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Host microenvironment in breast cancer development: extracellular matrix-stromal cell contribution to neoplastic phenotype of epithelial cells in the breast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Rapid onset of apoptosis in vitro follows disruption of beta 1-integrin/matrix interactions in human colonic crypt cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

1 reference

7 January 2021

Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Rho-stimulated contractility contributes to the fibroblastic phenotype of Ras-transformed epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208993

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208993

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Dimensions Publication ID

19 September 2017

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1 reference