(Q40380432)

20 September 2017

title

Mutations in the TLR3 signaling pathway and beyond in adult patients with herpes simplex encephalitis (English)

1 reference

20 September 2017

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E Bach

4

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Mette Christiansen

object named as

M Christiansen

8

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Lars Østergaard

object named as

L Østergaard

6

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author name string

N Mørk

1

1 reference

20 September 2017

E Kofod-Olsen

2

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20 September 2017

K B Sørensen

3

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20 September 2017

T F Ørntoft

5

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20 September 2017

S R Paludan

7

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20 September 2017

T H Mogensen

9

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20 September 2017

publication date

29 October 2015

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20 September 2017

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20 September 2017

volume

16

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20 September 2017

issue

8

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20 September 2017

page(s)

552-566

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TLR3 deficiency in patients with herpes simplex encephalitis

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Recognition of herpesviruses by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Severe herpesvirus infections in an adolescent without natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Type I interferon production during herpes simplex virus infection is controlled by cell-type-specific viral recognition through Toll-like receptor 9, the mitochondrial antiviral signaling protein pathway, and novel recognition systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

TLR2 and TLR9 synergistically control herpes simplex virus infection in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

IFI16 is an innate immune sensor for intracellular DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Herpes simplex virus encephalitis in human UNC-93B deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

NEMO is a key component of NF-κB- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Primary immunodeficiencies: a field in its infancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

A patient with tyrosine kinase 2 deficiency without hyper-IgE syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Pathogen recognition and inflammatory signaling in innate immune defenses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Essential role of IPS-1 in innate immune responses against RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

VISA is an adapter protein required for virus-triggered IFN-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Innate antiviral signalling in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Age-dependent Mendelian predisposition to herpes simplex virus type 1 encephalitis in childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

TLR3 deficiency in herpes simplex encephalitis: high allelic heterogeneity and recurrence risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Cell type-dependent requirement of autophagy in HSV-1 antiviral defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Immunodeficiency mutation databases (IDbases).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

KEGG: kyoto encyclopedia of genes and genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Data, information, knowledge and principle: back to metabolism in KEGG

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

A general framework for estimating the relative pathogenicity of human genetic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26513235

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/GENE.2015.46

1 reference

20 September 2017

1 reference