(Q28266613)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

Michael J Ciancanelli

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Satoshi Okada

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Alireza Mahdaviani

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Davood Mansouri

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Cindy S Ma

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Aurélie Cobat

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Che Kang Lim

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Mikael Sundin

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Rabih Halwani

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Bertrand Boisson

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Mélanie Migaud

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Caroline Deswarte

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Laia Alsina

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Valérie Cormier-Daire

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Stefan Rose-John

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Anne Puel

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Damien Chaussabel

48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Stuart Tangye

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Jacinta Bustamante

52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Jean-Laurent Casanova

53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Stephanie Boisson-Dupuis

54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

44

Lennart Hammarstrom

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Sara S Kilic

6

1 reference

ORCID Public Data File 2021

Bernhard Fleckenstein

40

object named as

Bernhard Fleckenstein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

47

Laurent Abel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

43

Capucine Picard

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

8

Shigeaki Nonoyama

1 reference

22 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

6

Sara Sebnem Kilic

1 reference

22 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

37

Daniel Kotlarz

1 reference

22 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

1

Alexandra Y Kreins

1 reference

22 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

26

Danielle T Avery

1 reference

22 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

4

Xiao-Fei Kong

1 reference

22 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

5

Noé Ramírez-Alejo

1 reference

22 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

50

Yoshiyuki Minegishi

1 reference

22 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

Ruben Martinez-Barricarte

33

object named as

Ruben Martinez-Barricarte

1 reference

22 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

10

Fatima Ailal

1 reference

22 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

31

Yuval Itan

1 reference

22 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

Jamila El Baghdadi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Aziz Bousfiha

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Elma Nievas

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Geetha Rao

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Andrea Bernasconi

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Hye Sun Kuehn

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Julie Niemela

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Jennifer Stoddard

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Paul Deveau

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Safa El Azbaoui

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Ayoub Sabri

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Audrey V Grant

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Dusan Bogunovic

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Marcela Moncada-Velez

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Christoph Klein

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Ingrid Muller-Fleckenstein

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Saleh Al-Muhsen

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Sergio D Rosenzweig

49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

language of work or name

English

0 references

publication date

24 August 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

22 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

212

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

1641-1662

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

22 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4577846/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Mendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

STAT2 deficiency and susceptibility to viral illness in humans

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Hyper-IgE syndrome update

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Janus kinases in immune cell signaling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

STAT3 mutations in the hyper-IgE syndrome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Interferons, interferon-like cytokines, and their receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

A natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Interleukin-12 receptor beta1 deficiency in a patient with abdominal tuberculosis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Hyper-IgE syndrome with recurrent infections--an autosomal dominant multisystem disorder

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

How cells respond to interferons

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

TYK2 kinase activity is required for functional type I interferon responses in vivo

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

IL-12Rβ1 deficiency in two of fifty children with severe tuberculosis from Iran, Morocco, and Turkey

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Jaks and STATs: biological implications

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Advances in IL-21 biology - enhancing our understanding of human disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Inherited and acquired immunodeficiencies underlying tuberculosis in childhood

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Targeted NGS: A Cost-Effective Approach to Molecular Diagnosis of PIDs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Human IL-21 and IL-21R deficiencies: two novel entities of primary immunodeficiency.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

HGCS: an online tool for prioritizing disease-causing gene variants by biological distance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Clinical features of Candidiasis in patients with inherited interleukin 12 receptor β1 deficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Immunology taught by human genetics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

The genetic theory of infectious diseases: a brief history and selected illustrations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

The human gene connectome as a map of short cuts for morbid allele discovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Autosomal dominant STAT3 deficiency and hyper-IgE syndrome: molecular, cellular, and clinical features from a French national survey

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Inborn errors of human JAKs and STATs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

The JAK-STAT pathway at twenty

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

A patient with tyrosine kinase 2 deficiency without hyper-IgE syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

IL-10 and IL-10 receptor defects in humans.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

A critical role for STAT3 transcription factor signaling in the development and maintenance of human T cell memory

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Recent insights into the pathobiology of innate immune deficiencies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Tyrosine kinase 2 (TYK2) in cytokine signalling and host immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Accounting for genetic heterogeneity in homozygosity mapping: application to Mendelian susceptibility to mycobacterial disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Whole-exome sequencing-based discovery of STIM1 deficiency in a child with fatal classic Kaposi sarcoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

A novel form of human STAT1 deficiency impairing early but not late responses to interferons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Pathogenesis of hyper IgE syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

A partial form of recessive STAT1 deficiency in humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

IL-21 is required to control chronic viral infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Hyper IgE syndrome: an update on clinical aspects and the role of signal transducer and activator of transcription 3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Recurrent staphylococcal cellulitis and subcutaneous abscesses in a child with autoantibodies against IL-6.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Human primary immunodeficiencies of type I interferons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Human complete Stat-1 deficiency is associated with defective type I and II IFN responses in vitro but immunity to some low virulence viruses in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Roles of interleukin-6 in activation of STAT proteins and recruitment of neutrophils during Escherichia coli pneumonia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Endogenous interleukin-6 plays a crucial protective role in streptococcal toxic shock syndrome via suppression of tumor necrosis factor alpha production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Full house: 12 receptors for 27 cytokines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Low penetrance, broad resistance, and favorable outcome of interleukin 12 receptor beta1 deficiency: medical and immunological implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Genetic dissection of immunity to mycobacteria: the human model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Partial impairment of cytokine responses in Tyk2-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia

29 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

29 September 2017

https://api.crossref.org/works/10.1084%2FJEM.20140280

Interleukin-6 is required for a protective immune response to systemic Escherichia coli infection

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

The Janus protein tyrosine kinases in hematopoietic cytokine signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Jaks and Stats in signaling by the cytokine receptor superfamily

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Severe impairment of IFN-γ and IFN-α responses in cells of a patient with a novel STAT1 splicing mutation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

A vital role for interleukin-21 in the control of a chronic viral infection

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

Bacillus Calmette Guérin triggers the IL-12/IFN-γ axis by an IRAK-4- and NEMO-dependent, non-cognate interaction between monocytes, NK, and T lymphocytes

2 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140280

IL-10 is required for optimal CD8 T cell memory following Listeria monocytogenes infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140280

IL-21R on T cells is critical for sustained functionality and control of chronic viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140280

Infant colitis—it's in the genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140280

Tyk2 deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140280

Exome sequencing identifies novel compound heterozygous mutations of IL-10 receptor 1 in neonatal-onset Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140280

Suppression of elevations in serum C reactive protein levels by anti-IL-6 autoantibodies in two patients with severe bacterial infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140280

A heritable defect in IL-12 signaling in B10.Q/J mice. I. In vitro analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140280

Automated minimization of steric clashes in protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140280

A heritable defect in IL-12 signaling in B10.Q/J mice. II. Effect on acute resistance to Toxoplasma gondii and rescue by IL-18 treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140280

Reduced adrenal response and increased mortality after systemic Klebsiella pneumoniae infection in interleukin-6-deficient mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577846

A protective role for IL-6 in staphylococcal microbial keratitis

27 November 2018

1 reference

12 December 2020

IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology

1 reference

12 December 2020

Pseudomonas aeruginosa keratitis in IL-6-deficient mice

1 reference

12 December 2020

Single-cell phospho-protein analysis by flow cytometry

1 reference

12 December 2020

Partial impairment of interleukin-12 (IL-12) and IL-18 signaling in Tyk2-deficient mice

1 reference

12 December 2020

Expression of Tyk2 in dendritic cells is required for IL-12, IL-23, and IFN-gamma production and the induction of Th1 cell differentiation

1 reference

12 December 2020

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

1 reference

12 December 2020

Inflammatory Bowel Disease With Lethal Disease Course Caused by a Nonsense Mutation in BIRC4 Encoding X-Linked Inhibitor of Apoptosis Protein (XIAP)

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20140280

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26304966%20AND%20SRC:MED&resulttype=core&format=json