(Q40389337)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079140%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

The origin of C1A-C2 interdomain interactions in protein kinase Calpha (English)

1 reference

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5 January 2020

1

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5 January 2020

author name string

Jiyao Wang

2

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5 January 2020

Nichole R Blatner

3

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5 January 2020

John D Rafter

4

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5 January 2020

Diana Murray

5

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5 January 2020

Wonhwa Cho

6

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5 January 2020

language of work or name

English

0 references

publication date

3 August 2005

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079140%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

5 January 2020

published in

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5 January 2020

volume

280

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5 January 2020

issue

43

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5 January 2020

page(s)

36452-36463

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Multiple pathways control protein kinase C phosphorylation

5 January 2020

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Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters.

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Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains

21 January 2018

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Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta

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Solution structure of a cysteine rich domain of rat protein kinase C.

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Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester

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NMR structure of a protein kinase C-gamma phorbol-binding domain and study of protein-lipid micelle interactions

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Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR)

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Intramolecular occlusion of the diacylglycerol-binding site in the C1 domain of munc13-1.

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Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine

21 January 2018

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Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.

21 January 2018

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The molecular basis of differential subcellular localization of C2 domains of protein kinase C-alpha and group IVa cytosolic phospholipase A2.

21 January 2018

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Interaction of protein kinase C with phosphatidylserine. 2. Specificity and regulation

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Roles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity.

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Mutagenesis of the C2 domain of protein kinase C-alpha. Differential roles of Ca2+ ligands and membrane binding residues

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Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals

21 January 2018

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Regulation of PKC alpha activity by C1-C2 domain interactions

21 January 2018

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Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha.

21 January 2018

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Role of the lysine-rich cluster of the C2 domain in the phosphatidylserine-dependent activation of PKCalpha.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M506224200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079140%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference