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BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner.
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Europe PubMed Central
PMC publication ID
3258114
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
title
BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner
(English)
1 reference
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Europe PubMed Central
PMC publication ID
3258114
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193957%20AND%20SRC:MED&resulttype=core&format=json
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19 January 2020
author
Pablo Lara-Gonzalez
series ordinal
1
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Europe PubMed Central
PMC publication ID
3258114
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retrieved
19 January 2020
Onur Sen
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4
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Europe PubMed Central
PMC publication ID
3258114
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
Stephen S. Taylor
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5
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3258114
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retrieved
19 January 2020
author name string
Maria I F Scott
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2
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3258114
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193957%20AND%20SRC:MED&resulttype=core&format=json
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19 January 2020
Maria Diez
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3
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Europe PubMed Central
PMC publication ID
3258114
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
language of work or name
English
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publication date
22 December 2011
1 reference
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Europe PubMed Central
PMC publication ID
3258114
reference URL
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retrieved
19 January 2020
published in
Journal of Cell Science
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Europe PubMed Central
PMC publication ID
3258114
reference URL
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19 January 2020
volume
124
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3258114
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retrieved
19 January 2020
issue
Pt 24
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Europe PubMed Central
PMC publication ID
3258114
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
page(s)
4332-4345
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Europe PubMed Central
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3258114
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19 January 2020
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22 September 2017
The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase
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22 September 2017
Mutations of mitotic checkpoint genes in human cancers
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22 September 2017
Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage
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22 September 2017
Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.
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25 September 2017
How APC/C-Cdc20 changes its substrate specificity in mitosis
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17 June 2018
Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258114
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17 June 2018
Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor
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17 June 2018
Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.
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17 June 2018
BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258114
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17 June 2018
Spindle checkpoint function requires Mad2-dependent Cdc20 binding to the Mad3 homology domain of BubR1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258114
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17 June 2018
The conserved N-terminal region of the mitotic checkpoint protein BUBR1: a putative TPR motif of high surface activity
1 reference
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17 June 2018
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B.
1 reference
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17 June 2018
Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.
1 reference
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PubMed Central
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20 August 2018
The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258114
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20 August 2018
Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258114
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20 August 2018
Large-scale purification of the vertebrate anaphase-promoting complex/cyclosome.
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20 August 2018
Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20.
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PubMed Central
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20 August 2018
The mitotic checkpoint gene BubR1 has two distinct functions in mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258114
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20 August 2018
Functional analysis of the spindle-checkpoint proteins using an in vitro ubiquitination assay
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258114
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20 August 2018
The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/22193957
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1242/JCS.094763
1 reference
stated in
Europe PubMed Central
PMC publication ID
3258114
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
PMC publication ID
3258114
1 reference
stated in
Europe PubMed Central
PMC publication ID
3258114
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
PubMed publication ID
22193957
1 reference
stated in
Europe PubMed Central
PMC publication ID
3258114
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
ResearchGate publication ID
51920110
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