(Q40400655)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16002406%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16002406%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16002406%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Hong-Van Le

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16002406%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Andy J Minn

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16002406%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

language of work or name

English

0 references

publication date

6 July 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16002406%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

30 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16002406%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

280

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16002406%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16002406%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

32018-32025

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16002406%20AND%20SRC:MED&resulttype=core&format=json

PUMA, a novel proapoptotic gene, is induced by p53

30 December 2019

cites work

1 reference

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PUMA induces the rapid apoptosis of colorectal cancer cells

21 January 2018

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Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals

21 January 2018

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WAF1, a potential mediator of p53 tumor suppression

21 January 2018

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

21 January 2018

1 reference

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PUMA mediates the apoptotic response to p53 in colorectal cancer cells

21 January 2018

1 reference

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

21 January 2018

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p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

21 January 2018

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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

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Radiation-induced cell cycle arrest compromised by p21 deficiency

21 January 2018

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Live or let die: the cell's response to p53

21 January 2018

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Colon cancer: genomics and apoptotic events

21 January 2018

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The significance of unstable chromosomes in colorectal cancer.

21 January 2018

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Disruption of p53 in human cancer cells alters the responses to therapeutic agents

21 January 2018

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Protection against chemotherapy-induced cytotoxicity by cyclin-dependent kinase inhibitors (CKI) in CKI-responsive cells compared with CKI-unresponsive cells

21 January 2018

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A new quantitative assay for cytochrome c release in apoptotic cells.

21 January 2018

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Monoclonal antibodies to mitotic cells

21 January 2018

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

1 reference

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Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation

21 January 2018

1 reference

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Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504689200

Intracellular determination of activated caspases (IDAC) by flow cytometry using a pancaspase inhibitor labeled with FITC

21 January 2018

1 reference

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Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

21 January 2018

1 reference

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Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

21 January 2018

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CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

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Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

21 January 2018

1 reference

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Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic cata

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504689200

The mitotic spindle checkpoint is a critical determinant for topoisomerase-based chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504689200

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504689200

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504689200

Direct coupling of the cell cycle and cell death machinery by E2F.

21 January 2018

1 reference

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Gene expression changes in response to E2F1 activation.

21 January 2018

1 reference

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Differential regulation of E2F1 apoptotic target genes in response to DNA damage.

21 January 2018

1 reference

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Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

21 January 2018

1 reference

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Proliferation of cancer cells despite CDK2 inhibition.

21 January 2018

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Apoptosis genes and resistance to cancer therapy: what does the experimental and clinical data tell us?

21 January 2018

1 reference

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If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

21 January 2018

1 reference

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Chemotherapy-associated oxidative stress: impact on chemotherapeutic effectiveness

21 January 2018

1 reference

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Topoisomerase poisons: harnessing the dark side of enzyme mechanism.

21 January 2018

1 reference

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Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

21 January 2018

1 reference

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Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

21 January 2018

1 reference

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Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M504689200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16002406%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference