(Q40407604)

20 September 2017

Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage (English)

1 reference

20 September 2017

0 references

Michael Berger

1

1 reference

20 September 2017

Nathalie Stahl

series ordinal

2

1 reference

20 September 2017

Giannino Del Sal

series ordinal

3

1 reference

20 September 2017

Ygal Haupt

series ordinal

4

1 reference

20 September 2017

language of work or name

English

0 references

publication date

1 July 2005

1 reference

Molecular and Cellular Biology

20 September 2017

1 reference

20 September 2017

25

1 reference

20 September 2017

13

1 reference

20 September 2017

5380-5388

1 reference

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

20 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

22 September 2017

MDM2, an introduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

The peptidyl-prolyl isomerase Pin1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Prolyl isomerase Pin1 as a molecular target for cancer diagnostics and therapeutics

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Chk1 and Chk2 kinases in checkpoint control and cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

p53: an internal investigation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

The cellular response to p53: the decision between life and death

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Cell type-specific inhibition of p53-mediated apoptosis by mdm2.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

The polyproline region of p53 is required to activate apoptosis but not growth arrest.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Pin1 acts catalytically to promote a conformational change in Cdc25.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

A Role for the Polyproline Domain of p53 in Its Regulation by Mdm2

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156984

Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15964795

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

p53 mutations in bladder tumors from arylamine-exposed workers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15964795

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A novel p53 germline alteration identified in a late onset breast cancer kindred

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15964795

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.25.13.5380-5388.2005

1 reference

20 September 2017

1 reference

20 September 2017

PubMed publication ID

15964795

1 reference