(Q40412842)

English

Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway

scientific article published on September 2005

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scholarly article

1 reference

Europe PubMed Central

20 September 2017

Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway (English)

1 reference

Europe PubMed Central

20 September 2017

10

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Europe PubMed Central

20 September 2017

Kenneth C. Anderson

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object named as

Kenneth C Anderson

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Europe PubMed Central

20 September 2017

5

object named as

Shaji Kumar

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Europe PubMed Central

20 September 2017

author name string

Kenji Ishitsuka

1

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Europe PubMed Central

20 September 2017

Teru Hideshima

2

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Europe PubMed Central

20 September 2017

Makoto Hamasaki

3

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Europe PubMed Central

20 September 2017

Noopur Raje

4

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Europe PubMed Central

20 September 2017

Klaus Podar

6

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Europe PubMed Central

20 September 2017

Steven Le Gouill

7

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Europe PubMed Central

20 September 2017

Norihiko Shiraishi

8

1 reference

Europe PubMed Central

20 September 2017

Hiroshi Yasui

9

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Europe PubMed Central

20 September 2017

Yu-Zu Tai

11

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Europe PubMed Central

20 September 2017

Dharminder Chauhan

12

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Europe PubMed Central

20 September 2017

Robert Fram

13

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Europe PubMed Central

20 September 2017

Kazuo Tamura

14

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Europe PubMed Central

20 September 2017

Jugnu Jain

15

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Europe PubMed Central

20 September 2017

language of work or name

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publication date

1 September 2005

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20 September 2017

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Europe PubMed Central

20 September 2017

24

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20 September 2017

38

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20 September 2017

5888-5896

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Europe PubMed Central

20 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208739

0 references

Death without caspases, caspases without death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Studies on the mechanism of action of 2-beta-D-ribofuranosylthiazole-4-carboxamide--V. Factors governing the response of murine tumors to tiazofurin

1 reference

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21 January 2018

Mechanism of taxol-induced apoptosis in human SKOV3 ovarian carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Role of AIF in caspase-dependent and caspase-independent cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Antibodies against membrane interleukin 1 alpha activate accessory cells to stimulate proliferation of T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Lymphocyte-Selective Cytostatic and Immunosuppressive Effects of Mycophenolic Acid in Vitro: Role of Deoxyguanosine Nucleotide Depletion

1 reference

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21 January 2018

Inhibition of human caspases by peptide-based and macromolecular inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Induction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Caspase-independent cell death in T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

VX-497: a novel, selective IMPDH inhibitor and immunosuppressive agent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Caspase-independent cell death?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Guanine nucleotide depletion triggers cell cycle arrest and apoptosis in human neuroblastoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Mitomycin C induces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Thalidomide for patients with relapsed multiple myeloma after high-dose chemotherapy and stem cell transplantation: results of an open-label multicenter phase 2 study of efficacy, toxicity, and biological activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

A phase 2 study of bortezomib in relapsed, refractory myeloma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Tissue-differential expression of two distinct genes for human IMP dehydrogenase (E.C.1.1.1.205).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Benzamide riboside, a recent inhibitor of inosine 5'-monophosphate dehydrogenase induces transferrin receptors in cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Phase I clinical trial of the inosine monophosphate dehydrogenase inhibitor mycophenolate mofetil (cellcept) in advanced multiple myeloma patients.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Guanine ribonucleotide depletion inhibits T cell activation. Mechanism of action of the immunosuppressive drug mizoribine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

Cytotoxicity and cellular differentiation activity of methylenebis(phosphonate) analogs of tiazofurin and mycophenolic acid adenine dinucleotide in human cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

21 January 2018

The role of tumor necrosis factor alpha in the pathophysiology of human multiple myeloma: therapeutic applications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

7 January 2021

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inferred from DOI database lookup

Inosine-5'-monophosphate dehydrogenase: regulation of expression and role in cellular proliferation and T lymphocyte activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208739

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1208739

1 reference

https://api.fatcat.wiki/v0/release/sr3hym46zvcullmkxqrhivc3vm

30 July 2022

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release_sr3hym46zvcullmkxqrhivc3vm

1 reference

https://api.fatcat.wiki/v0/release/sr3hym46zvcullmkxqrhivc3vm

30 July 2022

based on heuristic

mapped directly with Wikidata item

1 reference

https://api.fatcat.wiki/v0/release/sr3hym46zvcullmkxqrhivc3vm

30 July 2022

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