(Q40413928)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15933740%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

The PI3K inhibitor LY294002 prevents p53 induction by DNA damage and attenuates chemotherapy-induced apoptosis (English)

1 reference

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12 January 2020

0 references

6

1 reference

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12 January 2020

author name string

J Bar

1

1 reference

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12 January 2020

N Lukaschuk

2

1 reference

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12 January 2020

A Zalcenstein

3

1 reference

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12 January 2020

S Wilder

4

1 reference

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12 January 2020

R Seger

5

1 reference

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12 January 2020

publication date

3 June 2005

1 reference

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Cell Death & Differentiation

12 January 2020

published in

1 reference

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12 January 2020

volume

12

1 reference

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12 January 2020

issue

12

1 reference

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12 January 2020

page(s)

1578-1587

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New approaches to understanding p53 gene tumor mutation spectra

12 January 2020

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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21 January 2018

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Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

21 January 2018

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Live or let die: the cell's response to p53

21 January 2018

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The p53-Mdm2 module and the ubiquitin system.

21 January 2018

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The role of p53 in chemosensitivity and radiosensitivity.

21 January 2018

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Control of apoptosis by p53.

21 January 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

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PIK3CA is implicated as an oncogene in ovarian cancer.

21 January 2018

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p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas

21 January 2018

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High frequency of mutations of the PIK3CA gene in human cancers

21 January 2018

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Targeting the PI3K-Akt pathway in human cancer: rationale and promise

21 January 2018

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MAPK pathways in radiation responses

21 January 2018

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Regulation of p53 target gene expression by cisplatin-induced extracellular signal-regulated kinase

21 January 2018

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Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress

21 January 2018

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Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

21 January 2018

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p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389.

21 January 2018

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ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation

21 January 2018

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Osmotic shock induces G1 arrest through p53 phosphorylation at Ser33 by activated p38MAPK without phosphorylation at Ser15 and Ser20.

21 January 2018

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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

21 January 2018

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A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

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HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

21 January 2018

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IGF-1 activates p21 to inhibit UV-induced cell death.

21 January 2018

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Novel PI analogues selectively block activation of the pro-survival serine/threonine kinase Akt.

21 January 2018

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ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK.

21 January 2018

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Hypoxia links ATR and p53 through replication arrest

21 January 2018

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Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells

21 January 2018

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ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

21 January 2018

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

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DNA double-strand breaks: signaling, repair and the cancer connection

21 January 2018

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Cisplatinum and taxol induce different patterns of p53 phosphorylation

21 January 2018

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Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

21 January 2018

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PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

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PUMA induces the rapid apoptosis of colorectal cancer cells

21 January 2018

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

21 January 2018

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21 January 2018

Surfing the p53 network

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Decision making by p53: life, death and cancer

21 January 2018

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Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.

21 January 2018

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p53 accumulates but is functionally impaired when DNA synthesis is blocked

21 January 2018

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PI3K inhibition in neonatal rat brain slices during and after hypoxia reduces phospho-Akt and increases cytosolic cytochrome c and apoptosis

21 January 2018

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Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/anoxia

21 January 2018

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Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast

21 January 2018

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Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices

21 January 2018

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Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation

21 January 2018

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Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope

21 January 2018

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Delta Np63 alpha expression is regulated by the phosphoinositide 3-kinase pathway.

21 January 2018

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p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

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HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.

21 January 2018

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Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

21 January 2018

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p53 facilitates pRb cleavage in IL-3-deprived cells: novel pro-apoptotic activity of p53.

21 January 2018

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p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

21 January 2018

1 reference

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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

21 January 2018

1 reference

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7 January 2021

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401677

7 January 2021

Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401677

7 January 2021

DNA damage induces phosphorylation of the amino terminus of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401677

7 January 2021

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401677

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401677

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15933740%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 January 2020

1022115597

0 references

1 reference