(Q40425026)

English

Combination of a hepatitis C virus NS3-NS4A protease inhibitor and alpha interferon synergistically inhibits viral RNA replication and facilitates viral RNA clearance in replicon cells

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scholarly article

1 reference

Europe PubMed Central

20 September 2017

Combination of a hepatitis C virus NS3-NS4A protease inhibitor and alpha interferon synergistically inhibits viral RNA replication and facilitates viral RNA clearance in replicon cells (English)

1 reference

Europe PubMed Central

20 September 2017

Hepatitis C virus

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Kai Lin

1

1 reference

Europe PubMed Central

20 September 2017

Ann D Kwong

2

1 reference

Europe PubMed Central

20 September 2017

Chao Lin

3

1 reference

Europe PubMed Central

20 September 2017

language of work or name

0 references

publication date

1 December 2004

1 reference

Europe PubMed Central

20 September 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

20 September 2017

48

1 reference

Europe PubMed Central

20 September 2017

4784-4792

1 reference

Europe PubMed Central

20 September 2017

12

1 reference

Europe PubMed Central

20 September 2017

Kinetic profile of a heterocyclic HCV replicon RNA synthesis inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Synergistic antiviral activity of human interferon combinations in the hepatitis C virus replicon system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase.

1 reference

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22 September 2017

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

1 reference

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22 September 2017

Inhibitors of hepatitis C virus NS3.4A protease: an overdue line of therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

National Institutes of Health Consensus Development Conference: management of hepatitis C: 2002.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Viruses and interferon: a fight for supremacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Mechanism of action of ribavirin in the combination treatment of chronic HCV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Effect of alpha interferon on the hepatitis C virus replicon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Synthesis of a novel hepatitis C virus protein by ribosomal frameshift

1 reference

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22 September 2017

Evidence for a new hepatitis C virus antigen encoded in an overlapping reading frame

1 reference

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22 September 2017

Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Efficient initiation of HCV RNA replication in cell culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Possible mechanisms of action and reasons for failure of antiviral therapy in chronic hepatitis C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

A second hepatitis C virus-encoded proteinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

NS3 is a serine protease required for processing of hepatitis C virus polyprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Expression and identification of hepatitis C virus polyprotein cleavage products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

The search for synergy: a critical review from a response surface perspective.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

22 September 2017

A three-dimensional model to analyze drug-drug interactions

1 reference

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22 September 2017

Alternate translation occurs within the core coding region of the hepatitis C viral genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

25 September 2017

A simple generalized equation for the analysis of multiple inhibitions of Michaelis-Menten kinetic systems.

1 reference

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17 June 2018

In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

20 August 2018

An NS3 serine protease inhibitor abrogates replication of subgenomic hepatitis C virus RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

20 August 2018

Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529208

20 August 2018

Identifiers

10.1128/AAC.48.12.4784-4792.2004

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

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