(Q40426082)

20 September 2017

title

Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron (English)

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20 September 2017

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5

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Bernhard Brüne

7

object named as

Bernhard Brüne

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20 September 2017

Melvin Callapina

1

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20 September 2017

Jie Zhou

2

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20 September 2017

Steffen Schnitzer

3

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20 September 2017

Eric Metzen

4

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20 September 2017

Joachim W Deitmer

6

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20 September 2017

language of work or name

English

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publication date

20 March 2005

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Experimental Cell Research

20 September 2017

published in

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20 September 2017

volume

306

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20 September 2017

issue

1

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20 September 2017

page(s)

274-284

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Oxygen sensing and molecular adaptation to hypoxia

20 September 2017

cites work

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How oxygen makes its presence felt

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A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

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Purification and characterization of hypoxia-inducible factor 1

7 January 2021

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

7 January 2021

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Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

7 January 2021

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

7 January 2021

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

7 January 2021

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

7 January 2021

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

7 January 2021

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A conserved family of prolyl-4-hydroxylases that modify HIF

7 January 2021

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Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors

7 January 2021

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

7 January 2021

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Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

7 January 2021

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Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases

7 January 2021

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Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling

7 January 2021

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Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5' enhancer

7 January 2021

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Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia

7 January 2021

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HIF-1alpha-prolyl hydroxylase: molecular target of nitric oxide in the hypoxic signal transduction pathway

7 January 2021

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Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

7 January 2021

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Role of nitric oxide in the regulation of HIF-1alpha expression during hypoxia

7 January 2021

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Nitric oxide and reactive oxygen species exert opposing effects on the stability of hypoxia-inducible factor-1alpha (HIF-1alpha) in explants of human pial arteries

7 January 2021

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Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Determination of the chelatable iron pool of isolated rat hepatocytes by digital fluorescence microscopy using the fluorescent probe, phen green SK.

7 January 2021

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Determination of the chelatable iron pool of single intact cells by laser scanning microscopy

7 January 2021

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7 January 2021

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The role of nitric oxide (NO) in stability regulation of hypoxia inducible factor-1alpha (HIF-1alpha).

7 January 2021

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Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling

7 January 2021

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Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.

7 January 2021

1 reference

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Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.02.018

Hypoxia-inducible factor 1alpha (HIF-1alpha) is a non-heme iron protein. Implications for oxygen sensing

7 January 2021

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The chelatable iron pool in living cells: a methodically defined quantity

7 January 2021

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Chronic exposure to nitric oxide alters the free iron pool in endothelial cells: role of mitochondrial respiratory complexes and heat shock proteins

7 January 2021

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10.1016/J.YEXCR.2005.02.018

7 January 2021

Identifiers

DOI

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20 September 2017

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