(Q40428553)

20 September 2017

title

Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells (English)

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20 September 2017

3

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20 September 2017

Takayuki Teruya

1

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20 September 2017

Siro Simizu

series ordinal

2

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20 September 2017

Hiroyuki Osada

series ordinal

4

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20 September 2017

language of work or name

English

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publication date

1 April 2005

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20 September 2017

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20 September 2017

volume

579

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20 September 2017

issue

11

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20 September 2017

page(s)

2463-2468

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Integrating genetic approaches into the discovery of anticancer drugs

20 September 2017

cites work

1 reference

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The anticancer natural product pironetin selectively targets Lys352 of alpha-tubulin.

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Amphidinolide h, a potent cytotoxic macrolide, covalently binds on actin subdomain 4 and stabilizes actin filament.

21 January 2018

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Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster

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Protein phosphatase 2A inhibitors, phoslactomycins. Effects on the cytoskeleton in NIH/3T3 cells

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Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

21 January 2018

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Protein phosphatase 2A: a panoply of enzymes.

21 January 2018

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Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits

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Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling

21 January 2018

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Dephosphorylation of Bcl-2 by protein phosphatase 2A results in apoptosis resistance

21 January 2018

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The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondria

21 January 2018

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Molecular mechanisms of the protein serine/threonine phosphatases

21 January 2018

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Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

21 January 2018

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Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1

21 January 2018

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Crystal structure of the complex between calyculin A and the catalytic subunit of protein phosphatase 1

21 January 2018

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Characterization of the PP2A alpha gene mutation in okadaic acid-resistant variants of CHO-K1 cells

21 January 2018

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The predicted beta12-beta13 loop is important for inhibition of PP2Acalpha by the antitumor drug fostriecin

21 January 2018

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Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

21 January 2018

1 reference

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Parallel purification of three catalytic subunits of the protein serine/threonine phosphatase 2A family (PP2A(C), PP4(C), and PP6(C)) and analysis of the interaction of PP2A(C) with alpha4 protein

21 January 2018

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Studies of new phosphate ester antifungal antibiotics phoslactomycins. II. Structure elucidation of phoslactomycins A to F.

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.42.1026

Identifiers

DOI

10.1016/J.FEBSLET.2005.03.049

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20 September 2017

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