(Q40429977)

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The crystal structure of the non-liganded 14-3-3sigma protein: insights into determinants of isoform specific ligand binding and dimerization

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Europe PubMed Central

PubMed publication ID

20 September 2017

The crystal structure of the non-liganded 14-3-3sigma protein: insights into determinants of isoform specific ligand binding and dimerization (English)

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20 September 2017

protein structure

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Joma K Joy

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20 September 2017

author name string

Anne Benzinger

1

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Europe PubMed Central

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20 September 2017

Grzegorz M Popowicz

2

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Europe PubMed Central

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20 September 2017

Sudipta Majumdar

4

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20 September 2017

Tad A Holak

5

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20 September 2017

Heiko Hermeking

6

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20 September 2017

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1 April 2005

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20 September 2017

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20 September 2017

15

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20 September 2017

4

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20 September 2017

219-227

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20 September 2017

The 14-3-3 cancer connection

1 reference

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The role of epigenetic inactivation of 14-3-3sigma in human cancer

1 reference

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p63 identifies keratinocyte stem cells

1 reference

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14-3-3sigma is a p53-regulated inhibitor of G2/M progression

1 reference

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High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer

1 reference

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Downregulation of 14-3-3sigma in ovary, prostate and endometrial carcinomas is associated with CpG island methylation.

1 reference

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21 January 2018

Prostate cancer is characterized by epigenetic silencing of 14-3-3sigma expression

1 reference

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Analysis of 14-3-3sigma expression in hyperproliferative skin diseases reveals selective loss associated with CpG-methylation in basal cell carcinoma

1 reference

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21 January 2018

Frequent and histological type-specific inactivation of 14-3-3sigma in human lung cancers

1 reference

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21 January 2018

Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma

1 reference

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21 January 2018

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290290

21 January 2018

The structural basis for 14-3-3:phosphopeptide binding specificity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290290

21 January 2018

Specificity of 14-3-3 isoform dimer interactions and phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290290

21 January 2018

How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis

1 reference

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21 January 2018

Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation

1 reference

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21 January 2018

14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)

1 reference

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21 January 2018

Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase

1 reference

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21 January 2018

14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome

1 reference

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21 January 2018

The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of Bax

1 reference

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21 January 2018

Crystal structure of the zeta isoform of the 14-3-3 protein

1 reference

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21 January 2018

Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways

1 reference

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21 January 2018

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290290

21 January 2018

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290290

21 January 2018

Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290290

21 January 2018

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290290

21 January 2018

Automated refinement of protein models

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290290

21 January 2018

Functional conservation of 14-3-3 isoforms in inhibiting bad-induced apoptosis

1 reference

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21 January 2018

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer

1 reference

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21 January 2018

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10.1038/SJ.CR.7290290

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Europe PubMed Central

PubMed publication ID

20 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

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