(Q40430279)

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Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15856023%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells (English)

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11 January 2020

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prostate cancer

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3

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11 January 2020

Ah-Ng Tony Kong

5

object named as

Ah-Ng Tony Kong

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11 January 2020

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Changjiang Xu

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11 January 2020

Guoxiang Shen

2

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11 January 2020

Céline Gélinas

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11 January 2020

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1 June 2005

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11 January 2020

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11 January 2020

24

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11 January 2020

4486-4495

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11 January 2020

28

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11 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208656

0 references

NF-kappaB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach

1 reference

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Natural products as targeted modulators of the nuclear factor-kappaB pathway

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Potent induction of carcinogen defence enzymes with sulforaphane, a putative prostate cancer chemopreventive agent.

1 reference

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21 January 2018

Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA binding

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Phenylethyl isothiocyanate induces apoptotic signaling via suppressing phosphatase activity against c-Jun N-terminal kinase

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Tyrosine phosphorylation of I kappa B alpha activates NF kappa B through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation.

1 reference

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21 January 2018

The IKK/NF-kappaB activation pathway-a target for prevention and treatment of cancer

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21 January 2018

Inhibition of carcinogenesis by isothiocyanates

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Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms.

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In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat.

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21 January 2018

Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

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21 January 2018

Modulatory properties of various natural chemopreventive agents on the activation of NF-kappaB signaling pathway

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Signal transduction events elicited by cancer prevention compounds

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21 January 2018

Inhibition of NF-kappaB essentially contributes to arsenic-induced apoptosis.

1 reference

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21 January 2018

Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced NF-kappaB activation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins

1 reference

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21 January 2018

Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions

1 reference

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21 January 2018

Aberrant rel/nfkb genes and activity in human cancer

1 reference

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21 January 2018

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

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21 January 2018

Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes

1 reference

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21 January 2018

Sulforaphane induces caspase-mediated apoptosis in cultured PC-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo

1 reference

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21 January 2018

Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells

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21 January 2018

Vegetables, fruit, and cancer prevention: a review

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21 January 2018

Mechanisms of constitutive NF-kappaB activation in human prostate cancer cells

1 reference

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21 January 2018

NF-kappaB activation in human prostate cancer: important mediator or epiphenomenon?

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21 January 2018

Flavopiridol inhibits NF-kappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9.

1 reference

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21 January 2018

Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis

1 reference

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21 January 2018

Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase

1 reference

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21 January 2018

Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis

1 reference

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21 January 2018

The role of nutrition in preventing prostate cancer: a review of the proposed mechanism of action of various dietary substances.

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21 January 2018

Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate

1 reference

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7 January 2021

based on heuristic

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Fruit and vegetable intakes and prostate cancer risk

1 reference

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7 January 2021

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The protein kinase C activator, phorbol ester, elicits disparate functional responses in androgen-sensitive and androgen-independent human prostatic cancer cells

1 reference

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7 January 2021

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Identifiers

10.1038/SJ.ONC.1208656

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11 January 2020

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24 November 2022

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11 January 2020

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