(Q40440792)

20 September 2017

title

Transcriptional targeting of acute hypoxia in the tumour stroma is a novel and viable strategy for cancer gene therapy (English)

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20 September 2017

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Ingram N

1

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20 September 2017

Porter CD

series ordinal

2

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20 September 2017

publication date

1 July 2005

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20 September 2017

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20 September 2017

volume

12

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20 September 2017

issue

13

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20 September 2017

page(s)

1058-1069

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302504

20 September 2017

exact match

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cites work

Treatment resistance of solid tumors: role of hypoxia and anemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

A conserved family of prolyl-4-hydroxylases that modify HIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Reduced growth in response to ganciclovir treatment of subcutaneous xenografts expressing HSV-tk in the vascular compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

In vivo efficacy of HSV-TK transcriptionally targeted to the tumour vasculature is augmented by combination with cytotoxic chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Retroviral hybrid LTR vector strategy: functional analysis of LTR elements and generation of endothelial cell specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Generation of a high titre retroviral vector for endothelial cell-specific gene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

The Eugene M. Landis Award Lecture 1996. Delivery of molecular and cellular medicine to solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Characterization of physiologically regulated vectors for the treatment of ischemic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Regulated expression of a foreign gene targeted to the ischaemic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Oxygen-sensitive enzyme-prodrug gene therapy for the eradication of radiation-resistant solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Oxygenation predicts radiation response and survival in patients with cervix cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Expression of hypoxia-inducible factor 1? in brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

Microvascular structure of benign and malignant tumors of the colon in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

7 January 2021

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

7 January 2021

The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

7 January 2021

Non-constant tumour blood flow--implications for therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

7 January 2021

High-titer packaging cells producing recombinant retroviruses resistant to human serum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302504

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302504

1 reference

Dimensions Publication ID

20 September 2017

1035822775

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1 reference