(Q40443928)

English

Distinct roles for p53 transactivation and repression in preventing UCN-01-mediated abrogation of DNA damage-induced arrest at S and G2 cell cycle checkpoints

scientific article published in May 2005

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scholarly article

1 reference

Europe PubMed Central

20 September 2017

Distinct roles for p53 transactivation and repression in preventing UCN-01-mediated abrogation of DNA damage-induced arrest at S and G2 cell cycle checkpoints (English)

1 reference

Europe PubMed Central

20 September 2017

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author name string

Aime A Levesque

1

1 reference

Europe PubMed Central

20 September 2017

Ethan A Kohn

2

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Europe PubMed Central

20 September 2017

Edward Bresnick

3

1 reference

Europe PubMed Central

20 September 2017

Alan Eastman

4

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Europe PubMed Central

20 September 2017

language of work or name

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publication date

1 May 2005

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20 September 2017

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Europe PubMed Central

20 September 2017

24

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20 September 2017

3786-3796

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20 September 2017

23

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Europe PubMed Central

20 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208451

0 references

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Retinoic acid activates p53 in human embryonal carcinoma through retinoid receptor-dependent stimulation of p53 transactivation function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

DNA Damage Induces p53-dependent Down-regulation of hCHK1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

p53 regulation of G(2) checkpoint is retinoblastoma protein dependent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Transcriptional repression mediated by the p53 tumour suppressor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Transcriptional repression by p53 through direct binding to a novel DNA element

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Abrogation of the S phase DNA damage checkpoint results in S phase progression or premature mitosis depending on the concentration of 7-hydroxystaurosporine and the kinetics of Cdc25C activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Mechanism by which caffeine potentiates lethality of nitrogen mustard

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Rapid destruction of human Cdc25A in response to DNA damage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Molecular biology. Untangling checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

21 January 2018

Cyclin-dependent kinases at the G1-S transition of the mammalian cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

7 January 2021

based on heuristic

inferred from DOI database lookup

Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-Y mediates the transcriptional inhibition of the cyclin B1, cyclin B2, and cdc25C promoters upon induced G2 arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

7 January 2021

based on heuristic

inferred from DOI database lookup

Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208451

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1208451

1 reference

Europe PubMed Central

20 September 2017

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release_gvpkvqmmtjggjarb6actetw6jy

1 reference

https://api.fatcat.wiki/v0/release/gvpkvqmmtjggjarb6actetw6jy

24 November 2022

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mapped directly with Wikidata item

1 reference

Europe PubMed Central

20 September 2017

ResearchGate publication ID

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