(Q40451780)

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Biodistribution of rAAV vectors following intraocular administration: evidence for the presence and persistence of vector DNA in the optic nerve and in the brain.

scientific article published on February 2005

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Europe PubMed Central

20 September 2017

Biodistribution of rAAV vectors following intraocular administration: evidence for the presence and persistence of vector DNA in the optic nerve and in the brain. (English)

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Europe PubMed Central

20 September 2017

Fabienne Rolling

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Fabienne Rolling

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Nathalie Provost

1

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20 September 2017

Guylène Le Meur

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Europe PubMed Central

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Michel Weber

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Europe PubMed Central

20 September 2017

Alexandra Mendes-Madeira

4

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Europe PubMed Central

20 September 2017

Guillaume Podevin

5

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Europe PubMed Central

20 September 2017

Yan Cherel

6

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20 September 2017

Marie-Anne Colle

7

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20 September 2017

Jack-Yves Deschamps

8

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Europe PubMed Central

20 September 2017

Philippe Moullier

9

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20 September 2017

Fabienne Rolling

10

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20 September 2017

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1 February 2005

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Molecular Therapy

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20 September 2017

11

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275-283

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2

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20 September 2017

Functional and structural recovery of the retina after gene therapy in the RPE65 null mutation dog.

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AAV-Mediated gene transfer slows photoreceptor loss in the RCS rat model of retinitis pigmentosa

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Recombinant adeno-associated virus serotype 4 mediates unique and exclusive long-term transduction of retinal pigmented epithelium in rat, dog, and nonhuman primate after subretinal delivery

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Persistent transgene product in retina, optic nerve and brain after intraocular injection of rAAV.

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Reporter expression persists 1 year after adeno-associated virus-mediated gene transfer to the optic nerve

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Intravitreal gene therapy reduces lysosomal storage in specific areas of the CNS in mucopolysaccharidosis VII mice.

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Gene transfer into the mouse retina mediated by an adeno-associated viral vector

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Adeno-associated virus gene transfer to mouse retina

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Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina

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Long-term protection of retinal structure but not function using RAAV.CNTF in animal models of retinitis pigmentosa

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Sustained tetracycline-regulated transgene expression in vivo in rat retinal ganglion cells using a single type 2 adeno-associated viral vector

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Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model

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Five recombinant simian immunodeficiency virus pseudotypes lead to exclusive transduction of retinal pigmented epithelium in rat.

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Targeted retrograde gene delivery for neuronal protection

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Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

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Direction of transneuronal transport of herpes simplex virus 1 in the primate motor system is strain-dependent

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Intravitreal injection of the attenuated pseudorabies virus PRV Bartha results in infection of the hamster suprachiasmatic nucleus only by retrograde transsynaptic transport via autonomic circuits.

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Intramuscular administration of recombinant adeno-associated virus 2 alpha-1 antitrypsin (rAAV-SERPINA1) vectors in a nonhuman primate model: safety and immunologic aspects

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Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1.

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Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

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Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity

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Factors influencing recombinant adeno-associated virus production

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7 January 2021

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10.1016/J.YMTHE.2004.09.022

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Europe PubMed Central

20 September 2017

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Europe PubMed Central

20 September 2017

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