(Q40458353)

English

Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion

scientific article published on 14 February 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

1 reference

based on heuristic

inferred from title

author name string

Yasunari Takada

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Yoshinori Kobayashi

2

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Bharat B Aggarwal

3

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

language of work or name

0 references

publication date

14 February 2005

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

number of pages

10

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

280

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

17

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

17203-17212

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Complementary and alternative medicine: opportunities and challenges for cancer management and research

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Antianoxic action of evodiamine, an alkaloid in Evodia rutaecarpa fruit

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Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP.

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Induction of mitotic arrest and apoptosis by evodiamine in human leukemic T-lymphocytes

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Evodiamine, a constituent of Evodiae Fructus, induces anti‐proliferating effects in tumor cells

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Intracellular Regulation of Evodiamine-Induced A375-S2 Cell Death

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Inhibitory effect of dehydroevodiamine and evodiamine on nitric oxide production in cultured murine macrophages

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Inhibition by evodiamine of hepatocyte growth factor-induced invasion and migration of tumor cells

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Screening of natural compounds for inhibitory activity on colon cancer cell migration

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Anti-invasive and metastatic activities of evodiamine

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Inhibitory effects of evodiamine on in vitro invasion and experimental lung metastasis of murine colon cancer cells

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Nuclear factor-kappaB: the enemy within

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Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells

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NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

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Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning

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Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

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ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein

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Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer

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Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

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The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

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21 January 2018

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

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Protein kinase C-zeta regulates transcription of the matrix metalloproteinase-9 gene induced by IL-1 and TNF-alpha in glioma cells via NF-kappa B

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NF-κB-mediated Induction ofmdr1bExpression by Insulin in Rat Hepatoma Cells

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21 January 2018

Isolation of evodiamine, a powerful cardiotonic principle, from Evodia rutaecarpa Bentham (Rutaceae).

1 reference

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Cigarette smoke condensate activates nuclear transcription factor-kappaB through phosphorylation and degradation of IkappaB(alpha): correlation with induction of cyclooxygenase-2.

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Genetic Deletion of the Tumor Necrosis Factor Receptor p60 or p80 Sensitizes Macrophages to Lipopolysaccharide-induced Nuclear Factor-κB, Mitogen-activated Protein Kinases, and Apoptosis

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Betulinic acid suppresses carcinogen-induced NF-kappa B activation through inhibition of I kappa B alpha kinase and p65 phosphorylation: abrogation of cyclooxygenase-2 and matrix metalloprotease-9.

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Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase

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21 January 2018

Flavopiridol inhibits NF-kappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9.

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Activators and target genes of Rel/NF-kappaB transcription factors

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Nuclear transcription factor-kappaB as a target for cancer drug development

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Missing pieces in the NF-kappaB puzzle

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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NF-kappaB activation: the I kappaB kinase revealed?

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Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex

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Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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Inhibition of JNK activation through NF-kappaB target genes

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Mechanisms by which IkappaB proteins control NF-kappaB activity

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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Role of collagenases in tumor cell invasion

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Role of the NF-kappaB signaling pathway and kappaB cis-regulatory elements on the IRF-1 and iNOS promoter regions in mycobacterial lipoarabinomannan induction of nitric oxide

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Differential IκB Kinase Activation and IκBα Degradation by Interleukin-1β and Tumor Necrosis Factor-α in Human U937 Monocytic Cells

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A cellular rescue team

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Identifiers

10.1074/JBC.M500077200

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

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