(Q40470332)

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Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patien

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scholarly article

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Europe PubMed Central

PubMed publication ID

20 September 2017

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patien (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

0 references

intensive care unit

1 reference

based on heuristic

inferred from title

piperacillin/tazobactam

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based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

pharmacodynamics

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based on heuristic

inferred from title

pharmacokinetics

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based on heuristic

inferred from title

Despoina Koulenti

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Despoina Koulenti

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Murat Akova

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Jason A. Roberts

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Jason A Roberts

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Jeffrey Lipman

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Jordi Rello

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Andrew Rhodes

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Steven C Wallis

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Steven C Wallis

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Joel M Dulhunty

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Joel Dulhunty

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Europe PubMed Central

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20 September 2017

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Jan J De Waele

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20 September 2017

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Therese Starr

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20 September 2017

Matteo Bassetti

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Matteo Bassetti

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20 September 2017

Kirsi-Maija Kaukonen

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Kirsi-Maija Kaukonen

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20 September 2017

Mohd-Hafiz Abdul-Aziz

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Mohd H Abdul-Aziz

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20 September 2017

author name string

George Dimopoulos

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20 September 2017

Claude Martin

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20 September 2017

Philippe Montravers

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20 September 2017

DALI Study Group

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20 September 2017

language of work or name

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publication date

3 October 2015

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20 September 2017

Journal of Antimicrobial Chemotherapy

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20 September 2017

71

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20 September 2017

1

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20 September 2017

196-207

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20 September 2017

Basic pharmacodynamics of antibacterials with clinical applications to the use of beta-lactams, glycopeptides, and linezolid

1 reference

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First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis

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Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution.

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Continuous beta-lactam infusion in critically ill patients: the clinical evidence

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Clinical outcomes with alternative dosing strategies for piperacillin/tazobactam: a systematic review and meta-analysis

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Prolonged infusion versus intermittent boluses of β-lactam antibiotics for treatment of acute infections: a meta-analysis

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Continuous versus intermittent infusions of antibiotics for the treatment of severe acute infections

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Optimal dosing of antibiotics in critically ill patients by using continuous/extended infusions: a systematic review and meta-analysis

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Clinical outcomes with extended or continuous versus short-term intravenous infusion of carbapenems and piperacillin/tazobactam: a systematic review and meta-analysis

1 reference

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21 January 2018

Does prolonged β-lactam infusions improve clinical outcomes compared to intermittent infusions? A meta-analysis and systematic review of randomized, controlled trials

1 reference

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21 January 2018

A systematic review on clinical benefits of continuous administration of beta-lactam antibiotics

1 reference

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21 January 2018

Continuous versus intermittent intravenous administration of antibiotics: a meta-analysis of randomised controlled trials

1 reference

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21 January 2018

DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic

1 reference

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Prediction of creatinine clearance from serum creatinine

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21 January 2018

Continuous infusion of beta-lactam antibiotics in severe sepsis: a multicenter double-blind, randomized controlled trial

1 reference

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21 January 2018

Clinical and microbiological efficacy of continuous versus intermittent application of meropenem in critically ill patients: a randomized open-label controlled trial.

1 reference

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21 January 2018

Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration

1 reference

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21 January 2018

Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: a randomised controlled trial of continuous infusion versus intermittent bolus administration.

1 reference

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21 January 2018

Alveolar concentrations of piperacillin/tazobactam administered in continuous infusion to patients with ventilator-associated pneumonia

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21 January 2018

Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams

1 reference

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21 January 2018

Applying pharmacokinetic/pharmacodynamic principles in critically ill patients: optimizing efficacy and reducing resistance development

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21 January 2018

Exposure to ceftobiprole is associated with microbiological eradication and clinical cure in patients with nosocomial pneumonia

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21 January 2018

Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections

1 reference

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21 January 2018

Augmented renal clearance, low β-lactam concentrations and clinical outcomes in the critically ill: an observational prospective cohort study

1 reference

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21 January 2018

Meropenem and piperacillin/tazobactam prescribing in critically ill patients: does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?

1 reference

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21 January 2018

Infectious disease: childhood meningitis may be preventable if we can afford it.

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Standard versus prolonged doripenem infusion for treatment of gram-negative infections

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21 January 2018

Clinical cure of ventilator-associated pneumonia treated with piperacillin/tazobactam administered by continuous or intermittent infusion

1 reference

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21 January 2018

Comparison of clinical cure rates in adults with ventilator-associated pneumonia treated with intravenous ceftazidime administered by continuous or intermittent infusion: a retrospective, nonrandomized, open-label, historical chart review

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21 January 2018

Clinical pharmacodynamics of antipseudomonal cephalosporins in patients with ventilator-associated pneumonia

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International study of the prevalence and outcomes of infection in intensive care units

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Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation

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Piperacillin penetration into tissue of critically ill patients with sepsis--bolus versus continuous administration?

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Pharmacokinetics of antibiotics in natural and experimental superficial compartments in animals and humans

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Risk factors for late-onset nosocomial pneumonia caused by Stenotrophomonas maltophilia in critically ill trauma patients

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21 January 2018

Identifiers

10.1093/JAC/DKV288

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

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