(Q40476872)

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Degradation of HER2/neu by apigenin induces apoptosis through cytochrome c release and caspase-3 activation in HER2/neu-overexpressing breast cancer cells.

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Europe PubMed Central

PubMed publication ID

20 September 2017

Degradation of HER2/neu by apigenin induces apoptosis through cytochrome c release and caspase-3 activation in HER2/neu-overexpressing breast cancer cells. (English)

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Europe PubMed Central

PubMed publication ID

20 September 2017

apoptotic process

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author name string

Tzong-Der Way

1

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Europe PubMed Central

PubMed publication ID

20 September 2017

Ming-Ching Kao

2

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20 September 2017

Jen-Kun Lin

3

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20 September 2017

language of work or name

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publication date

1 January 2005

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Europe PubMed Central

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20 September 2017

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Europe PubMed Central

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20 September 2017

579

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20 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

145-152

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Antiproliferative activity of flavonoids on several cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Specific protection against breast cancers by cyclin D1 ablation

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

The CARD domain: a new apoptotic signalling motif

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Reversion of v-H-ras-transformed NIH 3T3 cells by apigenin through inhibiting mitogen activated protein kinase and its downstream oncogenes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Apigenin Induces Apoptosis through Proteasomal Degradation of HER2/neu in HER2/neu-overexpressing Breast Cancer Cells via the Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Current status of the molecular mechanisms of anticancer drug-induced apoptosis. The contribution of molecular-level analysis to cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

AKT plays a central role in tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

ErbB2-overexpressing human mammary carcinoma cells display an increased requirement for the phosphatidylinositol 3-kinase signaling pathway in anchorage-independent growth

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Height and breast cancer risk--the bias of self-reported versus measured results. Comments on height and breast cancer risk, Tavani et al., Eur J Cancer 1998, 34, 543-547.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Molecular mechanisms for apigenin-induced cell-cycle arrest and apoptosis of hormone refractory human prostate carcinoma DU145 cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Untangling the ErbB signalling network

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Inhibition of protein-tyrosine kinase activity by flavanoids and related compounds

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.11.061

21 January 2018

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10.1016/J.FEBSLET.2004.11.061

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

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