(Q40477785)

20 September 2017

title

A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein. (English)

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20 September 2017

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3

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20 September 2017

4

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Christian Haass

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author name string

Armgard Uelhoff

series ordinal

1

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20 September 2017

Jörg Tatzelt

series ordinal

2

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20 September 2017

language of work or name

English

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publication date

21 December 2004

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Journal of Biological Chemistry

20 September 2017

published in

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20 September 2017

volume

280

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20 September 2017

issue

7

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20 September 2017

page(s)

5137-5140

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Prions: health scare and biological challenge.

20 September 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.C400560200

Prion diseases of humans and animals: their causes and molecular basis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

21 January 2018

Prion Protein Biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

A transmembrane form of the prion protein in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to Purkinje cell degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Two different neurodegenerative diseases caused by proteins with similar structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Polarized epithelial membrane traffic: conservation and plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Sorting GPI-anchored proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Lipid rafts and apical membrane traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Polarized secretion of beta-amyloid precursor protein and amyloid beta-peptide in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Basolateral secretion of amyloid precursor protein in Madin-Darby canine kidney cells is disturbed by alterations of intracellular pH and by introducing a mutation associated with familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Apical sorting of beta-secretase limits amyloid beta-peptide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Determinants of the in vivo folding of the prion protein. A bipartite function of helix 1 in folding and aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Geldanamycin restores a defective heat shock response in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Inhibition of complex glycosylation increases the formation of PrPsc

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Kinetics of prion protein accumulation in the CNS of mice with experimental scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

PrPC is sorted to the basolateral membrane of epithelial cells independently of its association with rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Glycophospholipid membrane anchoring provides clues to the mechanism of protein sorting in polarized epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

NEUROBIOLOGY:PrP's Double Causes Trouble

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.C400560200

Glycosylation differences between the normal and pathogenic prion protein isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

Protein and lipid sorting from thetrans–Golgi network to the plasma membrane in polarized cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400560200

21 January 2018

Identifiers

DOI

10.1074/JBC.C400560200

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20 September 2017

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