(Q40484829)

20 September 2017

title

The alpha 1 and alpha 6 subunit subtypes of the mammalian GABA(A) receptor confer distinct channel gating kinetics (English)

1 reference

20 September 2017

Janet L Fisher

1

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20 September 2017

language of work or name

English

0 references

publication date

7 October 2004

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20 September 2017

number of pages

16

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inferred from page(s)

published in

Journal of Physiology

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20 September 2017

volume

561

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20 September 2017

issue

Pt 2

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20 September 2017

page(s)

433-448

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Activation of GABA(A) receptors containing the alpha4 subunit by GABA and pentobarbital

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Structural elements near the C-terminus are responsible for changes in nicotinic receptor gating kinetics following patch excision

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Molecular and electrophysiological characterization of a allelic variant of the rat alpha 6 GABAA receptor subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Alpha1 and alpha6 subunits specify distinct desensitization, deactivation and neurosteroid modulation of GABA(A) receptors containing the delta subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Neonatal development of the rat visual cortex: synaptic function of GABAA receptor alpha subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Long-term plasticity of postsynaptic GABAA-receptor function in the adult brain: insights from the oxytocin neurone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Plasticity in fast synaptic inhibition of adult oxytocin neurons caused by switch in GABA(A) receptor subunit expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Role of the putative transmembrane segment M3 in gating of neuronal nicotinic receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-d-aspartate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

A mutation in the GABAA receptor alpha 1 subunit linked to human epilepsy affects channel gating properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Single channel properties of recombinant GABAA receptors containing gamma 2 or delta subtypes expressed with alpha 1 and beta 3 subtypes in mouse L929 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Dependence of the GABAA receptor gating kinetics on the alpha-subunit isoform: implications for structure-function relations and synaptic transmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Prolongation of hippocampal miniature inhibitory postsynaptic currents in mice lacking the GABA(A) receptor alpha1 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Expression of functional GABAA receptors in transfected L929 cells isolated by immunomagnetic bead separation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

GABA alpha6 receptors mediate midazolam-induced anxiolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Statistical methods for model discrimination. Applications to gating kinetics and permeation of the acetylcholine receptor channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Neurosteroid effects on GABAergic synaptic plasticity in hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Developmental change in GABAA receptor desensitization kinetics and its role in synapse function in rat cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Coupling of agonist binding to channel gating in the GABA(A) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

A cytoplasmic region determines single-channel conductance in 5-HT3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Drug interactions at GABA(A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Benzodiazepine-induced motor impairment linked to point mutation in cerebellar GABAA receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Methionine 286 in transmembrane domain 3 of the GABAA receptor beta subunit controls a binding cavity for propofol and other alkylphenol general anesthetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Activation and deactivation rates of recombinant GABA(A) receptor channels are dependent on alpha-subunit isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Cys-loop receptors: new twists and turns

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Kinetic determinants of agonist action at the recombinant human glycine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Cerebellar GABAA receptor selective for a behavioural alcohol antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Receptor system response kinetics reveal functional subtypes of native murine and recombinant human GABAA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Which GABAA-receptor subtypes really occur in the brain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Structure and gating mechanism of the acetylcholine receptor pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Bi-directional changes in the levels of messenger RNAs encoding gamma-aminobutyric acidA receptor alpha subunits after flurazepam treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Spillover-mediated transmission at inhibitory synapses promoted by high affinity alpha6 subunit GABA(A) receptors and glomerular geometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

NMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: model of pore architecture and channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Barbiturate interactions at the human GABAA receptor: dependence on receptor subunit combination

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Distinct deactivation and desensitization kinetics of recombinant GABAA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Subunit mutations affect ethanol actions on GABA(A) receptors expressed in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

GABAA/benzodiazepine receptor alpha 6 subunit mRNA in granule cells of the cerebellar cortex and cochlear nuclei: expression in developing and mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Gamma-aminobutyric acid increases the water accessibility of M3 membrane-spanning segment residues in gamma-aminobutyric acid type A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Acetylcholine receptor M3 domain: stereochemical and volume contributions to channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

An update on GABAA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Pentobarbital differentially modulates alpha1beta3delta and alpha1beta3gamma2L GABAA receptor currents

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Neurosteroids shift partial agonist activation of GABA(A) receptor channels from low- to high-efficacy gating patterns.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Oxytocin regulates neurosteroid modulation of GABA(A) receptors in supraoptic nucleus around parturition.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Agonist Trapping by GABAA Receptor Channels.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

GABA(A) receptor alpha1 subunit deletion prevents developmental changes of inhibitory synaptic currents in cerebellar neurons.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Functional correlation of GABA(A) receptor alpha subunits expression with the properties of IPSCs in the developing thalamus.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Relationship between a GABAA alpha 6 Pro385Ser substitution and benzodiazepine sensitivity.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Propofol and other intravenous anesthetics have sites of action on the gamma-aminobutyric acid type A receptor distinct from that for isoflurane.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

The role of alpha1 and alpha6 subtype amino-terminal domains in allosteric regulation of gamma-aminobutyric acida receptors

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Cerebellar gamma-aminobutyric acid type A receptors: pharmacological subtypes revealed by mutant mouse lines.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Alpha 6 and gamma 2 subunit antisense oligodeoxynucleotides alter gamma-aminobutyric acid receptor pharmacology in cerebellar granule neurons

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Properties of recombinant gamma-aminobutyric acid A receptor isoforms containing the alpha 5 subunit subtype.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Properties of putative cerebellar gamma-aminobutyric acid A receptor isoforms.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Developmental changes of inhibitory synaptic currents in cerebellar granule neurons: role of GABA(A) receptor alpha 6 subunit

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

gamma-Aminobutyric acid gating of Cl- channels in recombinant GABAA receptors

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Assembly of GABAA receptor subunits: analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene technique.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Chronic ethanol administration alters gamma-aminobutyric acidA receptor gene expression

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665367

Somato-synaptic variation of GABAA receptors in cultured murine cerebellar granule cells: investigation of the role of the α6 subunit

4 November 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.051839

Evidence of two populations of GABA(A) receptors in cerebellar granule cells in culture: different desensitization kinetics, pharmacology, serine/threonine kinase sensitivity, and localization

21 January 2018

1 reference

12 December 2020

Identification of a naturally occurring Pro385-Ser385 substitution in the GABAA receptor α6 subunit gene in alcoholics and healthy volunteers

1 reference

12 December 2020

Intraburst kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture

1 reference

12 December 2020

Assembly of GABAA receptor subunits: alpha 1 beta 1 and alpha 1 beta 1 gamma 2S subunits produce unique ion channels with dissimilar single-channel properties

1 reference

12 December 2020

Selective isolation of transiently transfected cells from a mammalian cell population with vectors expressing a membrane anchored single-chain antibody

1 reference

12 December 2020

Mode switching kinetics produced by a naturally occurring mutation in the cytoplasmic loop of the human acetylcholine receptor epsilon subunit

1 reference

12 December 2020

GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts

1 reference

12 December 2020

10.1113/JPHYSIOL.2003.051839

Identifiers

DOI

1 reference

release_kgqdiodfdve7rhvmlfja43vokm

20 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kgqdiodfdve7rhvmlfja43vokm

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1665367

0 references

1 reference