(Q40491235)

English

5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms

scientific article

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scholarly article

1 reference

Europe PubMed Central

21 September 2017

retracted paper

2 references

Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms (English)

1 reference

Europe PubMed Central

21 September 2017

apoptotic process

0 references

1 reference

based on heuristic

inferred from title

Regine Schneider-Stock

1

object named as

Regine Schneider-Stock

0 references

Hala Gali-Muhtasib

9

object named as

Hala Gali-Muhtasib

0 references

author name string

Regine Schneider-Stock

1

1 reference

Europe PubMed Central

21 September 2017

Mona Diab-Assef

2

1 reference

Europe PubMed Central

21 September 2017

Astrid Rohrbeck

3

1 reference

Europe PubMed Central

21 September 2017

Charlotte Foltzer-Jourdainne

4

1 reference

Europe PubMed Central

21 September 2017

Carsten Boltze

5

1 reference

Europe PubMed Central

21 September 2017

Roland Hartig

6

1 reference

Europe PubMed Central

21 September 2017

Peter Schönfeld

7

1 reference

Europe PubMed Central

21 September 2017

Albert Roessner

8

1 reference

Europe PubMed Central

21 September 2017

Hala Gali-Muhtasib

9

1 reference

Europe PubMed Central

21 September 2017

language of work or name

0 references

publication date

16 November 2004

1 reference

Europe PubMed Central

21 September 2017

Journal of Pharmacology and Experimental Therapeutics

1 reference

Europe PubMed Central

21 September 2017

312

1 reference

Europe PubMed Central

21 September 2017

525-536

1 reference

Europe PubMed Central

21 September 2017

2

1 reference

Europe PubMed Central

21 September 2017

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/S0092-8674(00)81656-6

DNA hypomethylation causes an increase in DNase-I sensitivity and an advance in the time of replication of the entire inactive X chromosome.

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Regulation of p53 in response to DNA damage

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Uncoupling of p21WAF1/CIP1/SDI1 mRNA and protein expression upon genotoxic stress

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

High Prognostic Value of p16INK4 Alterations in Gastrointestinal Stromal Tumors

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

GADD45 induction of a G2/M cell cycle checkpoint

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21(WAF1/CIP1/sdi1).

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Dissecting de novo methylation

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

p53-dependent apoptosis pathways.

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

The DNA methyltransferases of mammals

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

A phosphatase associated with metastasis of colorectal cancer

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells.

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Regulation of the G2/M transition by p53.

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Overexpression of cyclin B1 in human colorectal cancers

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Down-regulation of human DNA-(cytosine-5) methyltransferase induces cell cycle regulators p16(ink4A) and p21(WAF/Cip1) by distinct mechanisms

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

GADD45-induced cell cycle G2-M arrest associates with altered subcellular distribution of cyclin B1 and is independent of p38 kinase activity

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine.

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Impact of azacytidine on the quality of life of patients with myelodysplastic syndrome treated in a randomized phase III trial: a Cancer and Leukemia Group B study

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Low-dose 5-aza-2'-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patients

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

5-Azadeoxycytidine induced undercondensation in the giant X chromosomes of Microtus agrestis

1 reference

https://opencitations.net/index/api/v1/references/10.1124/JPET.104.074195

30 December 2023

Identifiers

10.1124/JPET.104.074195

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

ResearchGate publication ID

0 references

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