(Q44737509)

5 December 2017

title

The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine (English)

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5 December 2017

5

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5 December 2017

6

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5 December 2017

María Nieto

1

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5 December 2017

Enrique Samper

series ordinal

2

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5 December 2017

Mario F Fraga

series ordinal

3

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5 December 2017

Gonzalo González de Buitrago

series ordinal

4

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5 December 2017

language of work or name

English

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publication date

1 January 2004

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5 December 2017

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5 December 2017

volume

23

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5 December 2017

issue

3

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5 December 2017

page(s)

735-743

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Inhibition of DNA methylation and reactivation of silenced genes by zebularine

5 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

The role of p53 in determining sensitivity to radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

p53 mutations increase resistance to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

p53 loss and point mutations are associated with suppression of apoptosis and progression of CML into myeloid blastic crisis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

Single-step, multiple retroviral transduction of human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

DNA hypomethylation leads to elevated mutation rates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

S-adenosyl-L-homocysteine: a non-cytotoxic hypomethylating agent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Chromosomal Instability and Tumors Promoted by DNA Hypomethylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

High-performance capillary electrophoretic method for the quantification of 5-methyl 2'-deoxycytidine in genomic DNA: application to plant, animal and human cancer tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Induction of Tumors in Mice by Genomic Hypomethylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

The effects of 5-azacytidine and 5-azadeoxycytidine on chromosome structure and function: implications for methylation-associated cellular processes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Apoptosis and mitotic cell death: their relative contributions to normal-tissue and tumour radiation response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

p53 mutations in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Delayed DNA damage associated with mitotic catastrophe following X-irradiation of HeLa S3 cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Tumor spectrum analysis in p53-mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Cellular differentiation, cytidine analogs and DNA methylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Primary mouse fibroblasts deficient for c-Fos, p53 or for both proteins are hypersensitive to UV light and alkylating agent-induced chromosomal breakage and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Role of p53 in leukemogenesis of chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Suppression of high-fidelity double-strand break repair in mammalian chromosomes by pifithrin-alpha, a chemical inhibitor of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

DNA double-strand breaks trigger apoptosis in p53-deficient fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

P53 plays a protective role against UV- and cisplatin-induced apoptosis in transcription-coupled repair proficient fibroblasts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Mutations of the p53 gene in myelodysplastic syndrome and overt leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Mutation of E2F2 in Mice Causes Enhanced T Lymphocyte Proliferation, Leading to the Development of Autoimmunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

p19ARF links the tumour suppressor p53 to Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Induction of senescence by oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Clinical implications of p53: effect on prognosis, tumor progression and chemotherapy response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Nuclear Apaf-1 and cytochrome c redistribution following stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Loss of the maintenance methyltransferase, xDnmt1, induces apoptosis in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Predicting response to cancer chemotherapy: the role of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

A genome-wide survey of RAS transformation targets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207175

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207175

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5 December 2017

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