(Q40507314)

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PTEN permits acute increases in D3-phosphoinositide levels following TCR stimulation but inhibits distal signaling events by reducing the basal activity of Akt.

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3 January 2020

PTEN permits acute increases in D3-phosphoinositide levels following TCR stimulation but inhibits distal signaling events by reducing the basal activity of Akt (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15468057%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Stephen Bunnell

3

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3 January 2020

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Ronald L Wange

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Maria-Cristina Seminario

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3 January 2020

Patricia Precht

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3 January 2020

Sarah E Warren

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3 January 2020

Christa M Morris

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3 January 2020

Dennis Taub

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3 January 2020

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1 November 2004

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3 January 2020

European Journal of Immunology

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3 January 2020

34

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3 January 2020

11

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3 January 2020

3165-3175

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3 January 2020

The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

21 January 2018

Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

21 January 2018

Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

21 January 2018

Expression of Active Protein Kinase B in T Cells Perturbs Both T and B Cell Homeostasis and Promotes Inflammation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

21 January 2018

Phosphoinositide 3-kinases in T lymphocyte activation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

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Lipid phosphatases in the regulation of T cell activation: living up to their PTEN-tial

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of phosphatidylinositol 3-kinase blocks T cell antigen receptor/CD3-induced activation of the mitogen-activated kinase Erk2

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

PTEN expression in PTEN-null leukaemic T cell lines leads to reduced proliferation via slowed cell cycle progression

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

A molecular mechanism for the effect of lithium on development

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Glycogen synthase kinase-3 inhibits the DNA binding activity of NFATc

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

CREB is a regulatory target for the protein kinase Akt/PKB

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Synergy between signal transduction pathways is obligatory for expression of c-fos in B and T cell lines: implication for c-fos control via surface immunoglobulin and T cell antigen receptors

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of NF-kappaB by the Akt/PKB kinase

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphoinositide 3-kinase regulation of T cell receptor-mediated interleukin-2 gene expression in normal T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

The PTEN tumor suppressor protein inhibits tumor necrosis factor-induced nuclear factor kappa B activity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

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T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425206

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/EJI.200425206

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15468057%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15468057%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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